Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 4-(p-Tolyl)-2,2:6,2-terpyridine, is researched, Molecular C22H17N3, CAS is 89972-77-0, about Effect of substituent of terpyridines on the DNA-interaction of polypyridyl ruthenium(II) complexes.COA of Formula: C22H17N3.
An octahedral complexes of ruthenium with 2,9-dimethyl-1,10-phenanthroline (dmphen) and substituted terpyridine were synthesized. The RuII complexes were characterized by elemental analyses, thermogravimetric analyses, magnetic moment measurements, FTIR, electronic, 1H NMR and FAB mass spectra. The binding strength and mode of interaction of the complexes with Herring Sperm DNA was studied using absorption titration and viscosity measurement studies. Results suggest that the substituent on terpyridine ligand affects the binding mode and binding ability of the complexes. Effect of time and ionic strength on DNA cleavage ability of complex also was studied by gel electrophoresis. Results suggest that >200 mM concentration of NaCl decreases the cleavage ability of complex.
In some applications, this compound(89972-77-0)COA of Formula: C22H17N3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI