Discovery of 112068-01-6

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Application In Synthesis of (S)-Diphenyl(pyrrolidin-2-yl)methanol, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 112068-01-6

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Application In Synthesis of (S)-Diphenyl(pyrrolidin-2-yl)methanol, Which mentioned a new discovery about 112068-01-6

A study was conducted to demonstrate highly enantioselective synthesis of beta-amino acid derivatives by the Lewis base catalyzed hydrosilylation of betaenamino esters. It was found that these catalyst and its analogue displayed excellent activities and enantioselectivities in promoting hydrosilylation of N-aryl beta-enamino esters. N-picolinoylpyrrolidine derivatives and N-picolioylephedrine were also evaluated in hydrosilylation of (Z)-methyl 3-phenyl-3-(phenylamino)acrylate. The generality of the Lewis base organocatalyzed hydrosilylation of various beta-enamino esters were examined under the optimized conditions. It was observed that the catalytic system exhibited a high sensitivity to the N-substituents, while all the N-aryl beta-enamino esters underwent the hydrosilylation smoothly to give corresponding beta-amino esters.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Application In Synthesis of (S)-Diphenyl(pyrrolidin-2-yl)methanol, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 112068-01-6

Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI