18531-99-2, Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬Which mentioned a new discovery about 18531-99-2
A chiral phosphorus alkene ligand, synthetic method and the application of the asymmetric reaction in (by machine translation)
The invention relates to a chiral phosphorus alkene ligand, a synthesis method and application thereof in asymmetric reaction. Specifically, the invention discloses a chiral phosphorus alkene compound, which has a structural formula shown as formula I or formula II in the specification, wherein R<1>, R<1'>, R<2>, R<3>, R<2'>, R<3'>, R<4>, R<5> and R<6> are defined in the specification. The chiral phosphorus alkene compound can be prepared from chiral 2, 2′-binaphthol or its derivative as the starting material through two to four steps of reaction by means of four methods. The chiral phosphorus alkene compound can be used as a chiral ligand in asymmetric addition reaction of rhodium catalyzed boric acid and prochiral C=X (X=C, O, N) double bond, and can achieve good yield and enantioselectivity.
18531-99-2, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 18531-99-2
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI