Synthetic Route of C5H8O3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about An alternative synthesis of (S)-(+)-γ-hydroxymethyl-γ-butyrolactone from (D)-(+)-mannitol. Author is Takano, Seiichi; Goto, Emiko; Hirama, Michiyasu; Ogasawara, Kunio.
Dioxolane I (R = iodo), obtainable from D-mannitol in 5 steps, was treated with di-Et malonate in DMF in the presence of NaH to give 62.7% I [R = CH(CO2Et)2], which on treatment with equimolar amount of MgCl2 in refluxing AcNMe2 gave 95% title lactone II of excellent optical purity.
In addition to the literature in the link below, there is a lot of literature about this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Synthetic Route of C5H8O3, illustrating the importance and wide applicability of this compound(32780-06-6).
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI