So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Bondarenko, S. P.; Mrug, G. P.; Vinogradova, V. I.; Khilya, V. P.; Frasinyuk, M. S. researched the compound: (S)-3-(Piperidin-2-yl)pyridine( cas:494-52-0 ).Name: (S)-3-(Piperidin-2-yl)pyridine.They published the article 《Conjugation of the Alkaloid Anabasine to Coumarins》 about this compound( cas:494-52-0 ) in Chemistry of Natural Compounds. Keywords: anabasine formaldehyde aryl hydroxycoumarin regioselective Mannich aminomethylation; aryl hydroxycoumarinylmethyl anabasine preparation. We’ll tell you more about this compound (cas:494-52-0).
The possibility of using the alkaloid anabasine in Mannich aminomethylation of coumarins was studied. Anabasine-coumarin conjugates in which the benzopyrone core was conjugated to anabasine through a methylene linker were synthesized.
The article 《Conjugation of the Alkaloid Anabasine to Coumarins》 also mentions many details about this compound(494-52-0)Name: (S)-3-(Piperidin-2-yl)pyridine, you can pay attention to it, because details determine success or failure
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI