Downstream synthetic route of 119-91-5

119-91-5, As the paragraph descriping shows that 119-91-5 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.119-91-5,2,2′-Biquinoline,as a common compound, the synthetic route is as follows.

Example: Zetaeta(NuO3) 2 ¡¤ 6H20 (29.7 mg, 0.1 mmol), 2,2′-biquinoline (25.6 mg, 0.1 mmol), 2,2 -biphenyl diacid (24.0 mg, 0.1 mmol) and NaN3 (13.2 mg, 0.2 mmol), were added to a mixed solvent of 12 mL methanol and secondary deionized water (1:1 volume ratio), It was sealed in a 25 mL stainless steel container lined with tetrafluoroethylene, heated to 140 C for 3 days, and then slowly cooled to room temperature. After filtration, the filter cake was washed with diethyl ether and dried in air to obtain colorless massive crystals, the calculated yield based on Zn(N03)2¡¤6H20 was approximately 61%. This material was insoluble in water and other organic solvents.

119-91-5, As the paragraph descriping shows that 119-91-5 is playing an increasingly important role.

Reference£º
Patent; Anqing Teachers College; Xu Heng; Yan Da; Feng Xuejun; Chen Zhengxiang; Xiong Zhi; Huang Rongyi; (9 pag.)CN108017661; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI