Downstream synthetic route of 153-94-6

153-94-6, As the paragraph descriping shows that 153-94-6 is playing an increasingly important role.

153-94-6, H-D-Trp-OH is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

D-Tryptophan (100 g), and PTSA.H20 (186.28 g) were added to allyl alcohol (1000 ml) stirred at 25 to 35C, followed by addition of toluene (500ml). The resulting mixture was stirred at 80-95C till completion of reaction, as monitored by TLC. After completion, the mass was cooled, and 5% aqueous sodium bicarbonate solution was added to it. Extraction with ethyl acetate followed by separation and concentration of the organic layer gave a residue containing H-D-Trp-OAll (11). Yield: 108.01 g (90.3%) Purity: > 95% (HPLC)

153-94-6, As the paragraph descriping shows that 153-94-6 is playing an increasingly important role.

Reference£º
Patent; EMCURE PHARMACEUTICALS LIMITED; GURJAR, Mukund Keshav; TRIPATHY, Narendra Kumar; PRAMANIK, Chinmoy Mriganka; DESHPANDE, Ashish Pramod; (25 pag.)WO2017/178950; (2017); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI