Reference of 366-18-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 366-18-7, Name is 2,2′-Bipyridine, SMILES is C1(C2=NC=CC=C2)=NC=CC=C1, belongs to catalyst-ligand compound. In a article, author is Ruan, Shixiang, introduce new discover of the category.
Facile dehydration of primary amides to nitriles catalyzed by lead salts: The anionic ligand matters
The synthesis of nitrile under mild conditions was achieved via dehydration of primary amide using lead salts as catalyst. The reaction processes were intensified by not only adding surfactant but also continuously removing the only by-product, water from the system. Both aliphatic and aromatic nitriles can be prepared in this manner with moderate to excellent yields. The reaction mechanisms were obtained with high-level quantum chemical calculations, and the crucial role the anionic ligand plays in the transformations were revealed.
Reference of 366-18-7, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 366-18-7.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI