Chemistry is an experimental science, Safety of (1R,2R)-Cyclohexane-1,2-diamine, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 20439-47-8, Name is (1R,2R)-Cyclohexane-1,2-diamine
Matching the chirality of monodentate N-heterocyclic carbene ligands: A case study on well-defined palladium complexes for the asymmetric alpha-arylation of amides
(Chemical Equation Presented) N-Heterocyclic carbene ligands derived from C2-symmetric diamines with naphthyl side chains are introduced as chiral monodentate ligands, and their palladium complexes (NHC)Pd(cin)C) are prepared. These compounds exist as a mixture of diastereomers, and the palladium complexes can be successfully separated and their absolute stereochemistry assigned. When used in the asymmetric intramolecular alpha-arylation of amides, oxindoles with quaternary carbon centers can be obtained in high yield and selectivity when correctly matching the chirality of the NHC complexes.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Safety of (1R,2R)-Cyclohexane-1,2-diamine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 20439-47-8, in my other articles.
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI