A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Product Details of 18531-99-2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 18531-99-2, Name is (S)-[1,1′-Binaphthalene]-2,2′-diol, molecular formula is C20H14O2. In a Article, authors is Li, Lingjun，once mentioned of 18531-99-2
Medium Rings Bearing Bitriazolyls: Easily Accessible Structures with Superior Performance as Cu Catalyst Ligands
Benefiting from their unique properties, the development of structurally novel and easily accessible medium rings is of significant interest in the pharmaceutical industry and academic research. However, synthetic access to medium-ring scaffolds is very difficult due to their rigid skeleton and large-angle strains. In this paper, a new class of medium rings bearing bitriazolyls (MRBTs) was designed, synthesized, identified as a promising new skeleton ligand for the Cu(I)-catalyzed click reaction, and used in site-special modification of protein. One of the MRBTs, 3aa, exhibited a turnover number (TON) as high as 55 000 and dramatic accelerating effects (kobs = 1.95 M-1 s-1) and ranked among the most efficient ligands for copper-catalyzed alkyne and azide cycloaddition. Unlike the difficult access to other known medium rings, these 7-12-membered MRBTs can be prepared in straightforward, one-step manner from structurally diverse linear terminal diynes and azides. The unique accessibility and intriguing properties therefore imply their broad application perspectives.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 18531-99-2, help many people in the next few years.Product Details of 18531-99-2
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI