Flexible application of in synthetic route 32780-06-6

Although many compounds look similar to this compound(32780-06-6)Related Products of 32780-06-6, numerous studies have shown that this compound(SMILES:O=C1O[C@H](CO)CC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor, published in 1999-02-28, which mentions a compound: 32780-06-6, Name is (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, Molecular C5H8O3, Related Products of 32780-06-6.

5-Lipoxygenase inhibitor (-)-CMI-977 I is prepared as the (2S,5S) enantiomer in nine steps from (S)-glutamic acid, 4-fluorophenol, 3-butynol, and N,O-bis(phenoxycarbonyl)hydroxylamine, and in seven steps from (S)-(+)-hydroxymethyl-γ-butyrolactone.

Although many compounds look similar to this compound(32780-06-6)Related Products of 32780-06-6, numerous studies have shown that this compound(SMILES:O=C1O[C@H](CO)CC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI