Li, Sasa; Huang, Xia; Gao, Yunlong; Jin, Jian published their research in Organic Letters on August 12 ,2022. The article was titled 《Oxalamide/Amide Ligands: Enhanced and Copper-Catalyzed C-N Cross-Coupling for Triarylamine Synthesis》.COA of Formula: C18H14BrOP The article contains the following contents:
A new protocol for triarylamine synthesis was presented where a wide range of diarylamines couple smoothly with aryl bromides mediated by a copper oxalamide (or amide) catalytic system. Notably, a new non-C2-sym. 1-isoquinolinamide-based N,N-/N,O-bidentate ligand was introduced that could tolerate bulky diarylamines. Plenty of known optoelectronic functional mols. could be synthesized in good to excellent yields. The practicality of this C-N cross-coupling was illustrated by the gram-scale synthesis of a patented thermally activated delayed fluorescence emitter for organic light-emitting diodes. In the part of experimental materials, we found many familiar compounds, such as (3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1COA of Formula: C18H14BrOP)
(3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1) belongs to mono-phosphine Ligands.Phosphine ligands are the most significant class of ligands for cross-coupling because of the alterability of their electronic and steric properties. Ligands play a key role in stabilizing and activating the central metal atom and are used in reactions, such as transition metal catalyzed cross-coupling.COA of Formula: C18H14BrOP
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI