HPLC of Formula: 10212-04-1On March 25, 2013, Madalska, Martyna; Loennecke, Peter; Hey-Hawkins, Evamarie published an article in Organometallics. The article was 《1,2-Disubstituted Aryl-Based Ferrocenyl Phosphines》. The article mentions the following:
Ferrocenylaryl- or ferrocenylheteroarylphosphines [Fe{1-PPh2(spacer)-2-NMe2CH2C5H3}(C5H5)] (spacer = 1,4-phenylene (rac-6), 1,3-phenylene (rac-7), 4,4′-biphenylene (rac-8), 2,5-thienylene (rac-9)) were prepared in a facile two-step sequence starting with Negishi cross-coupling between N,N-dimethylaminomethylferrocene and aryl halide phosphine oxides, Br-spacer-P(O)Ph2, followed by reduction with trichlorosilane. All products were characterized spectroscopically (1H, 13C, and 31P NMR, MS, FTIR), and rac-6, the corresponding phosphine oxide rac-2, and rac-9 were also characterized by x-ray crystallog. Furthermore, the redox properties of rac-2-9 were studied by cyclic voltammetry. The experimental part of the paper was very detailed, including the reaction process of (3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1HPLC of Formula: 10212-04-1)
(3-Bromophenyl)diphenylphosphine oxide(cas: 10212-04-1) belongs to mono-phosphine Ligands.Phosphine ligands are the most significant class of ligands for cross-coupling because of the alterability of their electronic and steric properties. Ligands play a key role in stabilizing and activating the central metal atom and are used in reactions, such as transition metal catalyzed cross-coupling.HPLC of Formula: 10212-04-1
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI