Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent, Safety of (R)-[1,1′-Binaphthalene]-2,2′-diamine, Which mentioned a new discovery about 18741-85-0
An atom-economical multicomponent cascade reaction of salicylaldehydes, cyclohexanones and arylamines has been developed for the synthesis of three-ring fused chromans. This reaction was achieved through cooperative enamine-metal Lewis acid assisted Br°nsted acid catalysis, furnishing the products in excellent yields with good diastereoselectivity.
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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI