10534-59-5, Tetrabutylammonium acetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 3: Synthesis of tetrabutyl ammonium salt of (25)-pyrrolidin-2-yl-methyl {[(25, 5 f)-7- oxo-6-(sulfooxy)-l,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}carbamate: To a stirred solution of (25)-pyrrolidin-2-yl- methyl { [(25, 5R)-7-oxo-6-(hydroxy)-l,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl} carbamate (0.984 g, 0.002 mol) in dimethylformamide (10 ml) was added dimethylformamide sulfur trioxide complex (0.548 g, 0.0035 mol) in one portion under stirring at 10C. The reaction mass was stirred at the same temperature for 30 minutes and allowed to warm to room temperature. After 1 hour, a solution of tetrabutylammonium acetate (1.05 g, 0.0035 mol) in dicholoromethane (2 ml) was added to the reaction mixture under continuous stirring. After 1 hour of stirring the solvent from the reaction mixture was evaporated under reduced pressure to obtain an oily residue. The oily mass was co-evaporated with xylene (2×10 ml) to obtain thick mass. This mass was partitioned between dichloromethane (10 ml) and water (10 ml). The combined organic extracts were washed with water (3×10 ml) and dried over anhydrous sodium sulfate.The solvent was evaporated under reduced pressure and the resulting oily mass was triturated with ether (3×10 ml), each time the ether layer was decanted and finally the residue was concentrated under reduced pressure to obtain 1.2 g of the titled product as white foam in 80% yield., 10534-59-5
10534-59-5 Tetrabutylammonium acetate 82707, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Patent; WOCKHARDT LIMITED; TADIPARTHI, Ravikumar; PATIL, Vijaykumar Jagdishwar; KALE, Amol; SHAIKH, Mohammad Usman; PATEL, Mahesh Vithalbhai; (65 pag.)WO2016/116788; (2016); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI