With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
General procedure: The pentafluorinated beta-diketone ligand (3 mmol), NaOH(0.12 g, 3 mmol) and the auxiliary ligand (1 mmol) were dissolved in 30 mL ethanol and heated to 60 C under stirring. Then, the ethanolic solution of EuCl3¡¤6H2O(1 mmol) was added dropwise, and the reaction mixture was stirred at 60 C for 8 h. After cooling down, the yellow solid was precipitated and filtered off. The solidproduct was washed with deionized water and ethanol, and dried in vacuum. Yellow powder, yield 78%, mp 200-202 C; IR nu (KBr):3031(m), 2967 (m), 2843 (w), 1597 (s), 1572 (s), 1501 (s), 1258 (s), 1172 (s),1082 (m), 1013 (m), 930 (m), 845 (m), 789 (s), 588 (m), 508 (m) cm-1; 1H NMR(300 MHz, CDCl3):delta 3.70 (s, 3H, C=CH), 3.94 (s, 9H, OCH3),6.86 (br, 6H, Ar-H),7.61 (br, 6H, Ar-H), 7.96 (br, 2H, Bath-H), 8.17 (br, 4H, Bath-H), 8.58 (br, 2H,Bath-H), 8.73 (br, 4H, Bath-H), 9.24 (br, 2H, Bath-H), 12.10 (br, 2H, Bath-H) ppm.Anal. Calcd. for EuC60H40N2O9F15:C, 52.61; H, 2.94; N, 2.04; Eu, 11.09; Found C,52.94; H, 2.91; N, 2.09; Eu, 11.25.
The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Wan, Yupeng; Lyu, Heng; Du, Hengyi; Wang, Dunjia; Yin, Guodong; Research on Chemical Intermediates; vol. 45; 4; (2019); p. 1669 – 1687;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI