With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.33454-82-9,Lithium trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.
General procedure: To the solution of 2-Cl (186 mg, 0.25 mmol) dissolvedin5.0 mL of methanol/CH2Cl2 (1/9), a 5% aqueous solution of sodiumtetrafluoroborate (1.5 g, 0.41 mmol) was added. The solution was stirredat room temperature for 1 h. Reaction was monitored by Alumina(Al2O3) TLC plate in MeOH/CH2Cl2 (5/95); an Rf ~ 0.9 of product washigher than Rf ~ 0.5 of 2-Cl. The organic layer was passed through ashort Al2O3 flash column. The crude product was collected after solventswere removed. The product isolated as fine off white powder was obtainedafter recrystallization from isopropanol/ethyl acetate. Yield 70%;, 33454-82-9
33454-82-9 Lithium trifluoromethanesulfonate 3664839, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Article; Wang, Ren-Tzong; Jane Tsai, Suh-Jen; Lee, Gene-Hsiang; Lai, Chung K.; Dyes and Pigments; vol. 173; (2020);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI