4568-71-2, 3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a 2 L four-necked flask equipped with a stirrer and a nitrogen gas inlet tube, 301.7 g (1.12 g) of 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride Mol), ion exchanged water 300.3 g and sodium thiocyanate 91.6 g (1.43 mol), and the mixture was stirred at room temperature for 3 hours. After completion of the stirring, the organic layer was separated from the reaction solution separated into an aqueous layer and an organic layer. After washing the organic layer three times with 300 g of ion exchanged water, it was placed in a rotary evaporator and concentrated. The obtained concentrate was dried under reduced pressure, dissolved with 157.48 g of methanol, heated to 65 ¡ã C. and recrystallized by cooling. The obtained crystals were separated by filtration and dried under reduced pressure to give 3-benzyl-5- (2-hydroxyethyl) -4-methylthiazolium thiocyanate248.97 g (yield: 76percent) was obtained.
4568-71-2 3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride 2833352, acatalyst-ligand compound, is more and more widely used in various.
Reference£º
Patent; KOEI CHEMICAL COMPANY LIMITED; TAGATA, TSUYOSHI; KAWAMICHI, TAKEHIDE; SAITO, AYA; (17 pag.)JP5814080; (2015); B2;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI