5350-41-4, N,N,N-Trimethyl-1-phenylmethanaminium bromide is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5350-41-4, General procedure: Ammonium salt 6 (1 equiv.) was suspended in dry THF (0.05 M) andstirred at 40 ¡ãC. t-BuOK (4 equiv.) was added and the mixture was stirred vigorously. After 10 minutes 2 equiv. of aldehyde 2 were added and the mixture was stirred for 3 hours at 40 ¡ãC. The reaction was then quenched by addition of a half-saturated NaCl solution. After phase separation, the aqueous phase was extracted three times with DCM and the combined organic phases were dried with Na2SO4 and evaporated to dryness. Purification by columnchromatography (gradient of heptanes and EtOAc) gave the corresponding epoxides in the reported yields as a mixture of diastereomers.
5350-41-4 N,N,N-Trimethyl-1-phenylmethanaminium bromide 21449, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Article; Roiser, Lukas; Robiette, Raphael; Waser, Mario; Synlett; vol. 27; 13; (2016); p. 1963 – 1968;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI