7328-91-8, 2,2-Dimethylpropane-1,3-diamine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Pyridine-2-carbaldehyde (30 mmol, 3.21 g)And 2,2-dimethyl-1,3-propanediamine (15 mmol, 1.53 g)30mL of methanol mixed,After 7.0 hours at room temperature,Slowly add NaBH4 (120 mmol, 4.54 g) slowly while stirring in an ice-water bath Slowly warmed to 70 for 5 hours.Stop the reaction,Cool to room temperature,Rotate the reaction solution.Then 50mL CH2Cl2 dissolved, filtered, Filtrate spin dry,Have yellow oily sticky substance.After dissolving the above yellow oily dope in 30 mL of methanol,To this was added an equimolar amount of aqueous formaldehyde solution,After stirring at room temperature for 3 hours,The solvent was removed under reduced pressure,Isolated and purified by column chromatography to give 3,3-dimethyl-1,3-bis (2-picolyl) hexahydropyrimidine (3.96 g, yield 89percent)., 7328-91-8
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Reference£º
Patent; Henan University of Technology; Yang Liangru; Mai Wenpeng; Mao Pu; Xiao Yongmei; Yuan Jinwei; Qu Lingbo; (12 pag.)CN104744519; (2017); B;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI