Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.73-22-3, Name is H-Trp-OH, SMILES is N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O, belongs to catalyst-ligand compound. In a document, author is McGuire, Ryan T., introduce the new discover, Product Details of 73-22-3.
Nickel-Catalyzed N-Arylation of Fluoroalkylamines
The Ni-catalyzed N-arylation of beta-fluoroalkylamines with broad scope is reported for the first time. Use of the air-stable pre-catalyst (PAd2-DalPhos)Ni(o-tol)Cl allows for reactions to be conducted at room temperature (25 degrees C, NaOtBu), or by use of a commercially available dual-base system (100 degrees C, DBU/NaOTf), to circumvent decomposition of the N-(beta-fluoroalkyl)aniline product. The mild protocols disclosed herein feature broad (hetero)aryl (pseudo)halide scope (X=Cl, Br, I, and for the first time phenol-derived electrophiles), encompassing base-sensitive substrates and enantioretentive transformations, in a manner that is unmatched by any previously reported catalyst system.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 73-22-3 is helpful to your research. Product Details of 73-22-3.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI