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On the origin of copper(i) catalysts from copper(ii) precursors in C-N and C-O cross-couplings
CuII precursors ligated to phenanthrolines are reduced in situ by alcohols or amines in the presence of a base (Cs2CO3) to generate CuI species which are active catalysts in C-N and C-O cross-coupling reactions. The conversion CuII ? CuI has been evidenced and monitored by UV-vis and NMR spectroscopy.
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Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI