Properties and Exciting Facts About 32780-06-6

Here is a brief introduction to this compound(32780-06-6)Category: catalyst-ligand, if you want to know about other compounds related to this compound(32780-06-6), you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called A highly stereoselective synthesis of anti-HIV 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxynucleosides, published in 1992-07-03, which mentions a compound: 32780-06-6, Name is (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, Molecular C5H8O3, Category: catalyst-ligand.

A general total synthetic method for the stereocontrolled synthesis of 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxynucleosides, is presented. Introduction of an α-phenylselenenyl group at the 2-position of 2,3-dideoxyribosyl acetate directs the glycosyl bond formation to give ≥95% β-isomer. This 2′-phenylselenenyl nucleoside may be converted to either the 2′,3′-dideoxynucleoside by treatment with n-Bu3SnH and Et3B at room temperature or to the unsaturated derivative by treatment with H2O2/cat. pyridine. The application of this method to the syntheses of pyrimidines (ddU, ddT, ddC), 6-substituted purines (ddA, ddT, 6-chloro-ddP, N6-Me-ddA), and 2,6-disubstituted pruines(2-F-ddA, 6-chloro-2-amino-ddP) as well as selected 2′,3′-didehydro-2′,3′-dideoxy derivatives, is reported.

Here is a brief introduction to this compound(32780-06-6)Category: catalyst-ligand, if you want to know about other compounds related to this compound(32780-06-6), you can read my other articles.

Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI