In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 1660-93-1, name is 3,4,7,8-Tetramethyl-1,10-phenanthroline, introducing its new discovery. Quality Control of: 3,4,7,8-Tetramethyl-1,10-phenanthroline
Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-alpha
The novel iridium(III) complex 1 was verified as a potent inhibitor of the TNF-alpha-TNFR protein-protein interaction in vitro and in cellulo. The iridium(III) center plays a critical role in organizing the structure of the bioactive metal complex, as the isolated ligands were found to be completely inactive. Both iridium enantiomers inhibited TNF-alpha-induced NF-kappaB activity and TNF-alpha-TNFR binding. 1 represents a promising scaffold for the further development of more potent organometallic TNF-alpha inhibitors.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1660-93-1 is helpful to your research. Quality Control of: 3,4,7,8-Tetramethyl-1,10-phenanthroline
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI