Synthetic Route of 76089-77-5, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 76089-77-5, Name is Cerium(III) trifluoromethanesulfonate, molecular formula is C3CeF9O9S3. In a Article£¬once mentioned of 76089-77-5
Aldehydes vs aldimines. Unprecedented aldimine-selective nucleophilic additions in the coexistence of aldehydes using a lanthanide salt as a Lewis acid catalyst
It is well-recognized that aldimines are less reactive than aldehydes toward nucleophilic additions. In this paper, an unprecedented change in the reactivity is described: preferential reactions of aldimines over aldehydes in nucleophilic additions using a lanthanide salt as a Lewis acid catalyst. In the presence of a catalytic amount of ytterbium triflate (Yb(OTf)3), only aldimines reacted with silyl enol ethers, ketene silyl acetals, allyltributylstannane, or cyanotrimethylsilane to afford the corresponding adducts in high yields, even in the coexistence of aldehydes. Selective formation of an aldimine-Yb(OTf)3 complex rather than an aldehyde-Yb(OTf)3 complex was indicated by 13C NMR analyses. While this report demonstrates the effective use of Lewis acids in organic synthesis, the basic idea of changing reactivity as shown here will be widely applied to many other nucleophilic additions.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Synthetic Route of 76089-77-5, you can also check out more blogs about76089-77-5
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI