Chemistry is an experimental science, name: H-D-Pro-OH, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 344-25-2, Name is H-D-Pro-OH
Cycloforskamide, a cytotoxic macrocyclic peptide from the sea slug Pleurobranchus forskalii
A macrocylic dodecapeptide, cycloforskamide, was isolated from the sea slug Pleurobranchus forskalii, collected off Ishigaki Island, Japan. Its planar structure was deduced by extensive NMR analyses and was further confirmed by MS/MS fragmentation analyses. Finally, the absolute configuration was determined by total hydrolysis and chiral-phase gas chromatographic analysis. This novel dodecapeptide contains three d-amino acids and three thiazoline heterocycles and exhibits cytotoxicity against murine leukemia P388 cells, with an IC 50 of 5.8 muM.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: H-D-Pro-OH, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 344-25-2, in my other articles.
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI