Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 848821-76-1, molcular formula is C21H15F12NO, introducing its new discovery. HPLC of Formula: C21H15F12NO
The present study was undertaken to illustrate the anti-inflammatory activity of seahorse (Hippocampus trimaculatus) extract in carrageenaninduced rat paw oedema model. Molecular docking study was executed with COX-2 and heme oxygenase inhibitor complexes to illustrate the interactions exhibited by seahorse extract metabolite with the target protein. Favourable interactions of seahorse extract metabolite with the active site residues of the COX-2 and heme oxygenase could be correlated with the potency and the compound is proved to be an anti-inflammatory agent as well as an antidote. In vitro anti-inflammatory activity by Human Red Blood Cell (HRBC) membrane stabilisation method was evaluated. Structure Activity Relationship (SAR) of the Cpd1-6 with various functional groups was also evaluated. Cpd6 with ketone, amine and four -CH3 found with best activity with a maximum percentage inhibition (Mean±SEM) 71.72±2.84 and IC50 17.89 mug/mL while Cpd3 with only -CH3 group showed a least activity of 33.24±4.41, IC50 94.38 mug/mL.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C21H15F12NO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 848821-76-1
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI