With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.100125-12-0,3,8-Dibromo-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
General procedure: A mixture of stoichiometric amounts of sodium tetrafluoroborate (0.110 g, 1.0 mmol) in 10 cm3 water and 3-bromo-phen (0.259 g, 1.0 mmol) in 40 cm3 ethanol was refluxed for 2 h. The mixture was cooled to room temperature and concentrated to nearly dry using a rotatory evaporator, and then the resulting precipitate 2 was filtered and washed by diethyl ether and dried in a vacuum. Yield: 0.28 g (75.9%).
100125-12-0, As the paragraph descriping shows that 100125-12-0 is playing an increasingly important role.
Reference£º
Article; Qian, Hui-Fen; Liu, Yuan; Tao, Tao; Gu, Ke-Hua; Yin, Gui; Huang, Wei; Inorganica Chimica Acta; vol. 405; (2013); p. 1 – 8;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI