With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.10534-59-5,Tetrabutylammonium acetate,as a common compound, the synthetic route is as follows.
10534-59-5, General procedure: A solution of H6buea (200 mg, 0.45 mmol) dissolved in 4 mL of anhydrous DMA was treated with solid KH (55 mg, 1.36 mmol) and stirred until gas evolution ceased. Fe(OAc)2 (79 mg, 0.45 mmol) was added to the pale yellow solution, and stirring was continued for 30 min. The resulting amber filtrate was treated with [Bu4N][OAc] (140 mg, 0.45 mmol) and stirred for 2 h, resulting in the precipitation of a white solid (305 mg) that was filtered, washed twice with Et2O, and dried under vacuum. The white solid was stirred in CH3CN for 1 h and filtered to remove KOAc (105 mg, 96%). The light yellow filtrate was concentrated to half its original volume and the slow addition of Et2O resulted in the formation of a white solid, which was then filtered, washed with Et2O, and dried under vacuum to afford 150 mg (47%) of the desired salt. [Bu4N]2[Fe(II)H22iPr]2 was prepared following a similar procedure to that of [Bu4N]2[Fe(II)H3buea]2 with H52iPr (150 mg, 0.37 mmol), KH (45 mg, 1.12 mmol), Fe(OAc)2 (66 mg, 0.37 mmol), and [Bu4N][OAc] (113 mg, 0.37 mmol). The amount of KOAc obtained was 105 mg (96% for 3 equiv) and 100 mg (42%) of [Bu4N]2[FeIIH22iPr] was isolated. FTIR (Nujol, cm-1) nu(NH) 3332, nu(CO) 1661, 1590, 1561, 1520. Repeated attempts to obtain a satisfactory elemental analysis were unsuccessful.
The synthetic route of 10534-59-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Lacy, David C.; Mukherjee, Jhumpa; Lucas, Robie L.; Day, Victor W.; Borovik; Polyhedron; vol. 52; (2013); p. 261 – 267;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI