With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.128143-89-5,4′-Chloro-2,2′:6′,2”-terpyridine,as a common compound, the synthetic route is as follows.
Compound M (18.00 g, 34.25 mmol) and compound N (12.23 g, 34.25 mmol) were completely dissolved in 300 ml of tetrahydrofuran in a 500 ml round-bottomed flask under nitrogen atmosphere, and 2M aqueous potassium carbonate solution (150 ml)Tetrakis- (triphenylphosphine) palladium (1.18 g, 1.02 mmol) was added thereto, followed by heating and stirring at 75C for 3 hours. The temperature was lowered to room temperature (23 ¡À 5 C), the water layer was removed, dried over anhydrous magnesium sulfate, concentrated under reduced pressure, and recrystallized from 120 ml of ethyl acetate to obtain Compound 10 (16.9 g, 74%
128143-89-5, 128143-89-5 4′-Chloro-2,2′:6′,2”-terpyridine 667748, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Patent; LG CHEMICAL LTD; LG Chem, Ltd.; YANG JUNG HOON; Yang Jeong-hun; LEE DONG HOON; Lee Dong-hun; HUH JUNG OH; Huh Jeong-o; JANG BOON JAE; Jang Bun-jae; HEO DONG UK; Huh Dong-uk; HAN MI YEON; Han Mi-yeon; YUN HEE KYUNG; Yoon Hui-gyeong; (47 pag.)KR2019/9704; (2019); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI