With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13093-04-4,N1,N6-Dimethylhexane-1,6-diamine,as a common compound, the synthetic route is as follows.
EXAMPLE III N,N’-Dimethyl-N,N’-hexamethylene-bis[3-(N,N-dibenzyl aminoxy)propionamide] A solution of 6.4 g of 3-(N,N-dibenzylaminoxy) propanoic acid in 25 ml of methylene chloride is admixed with 1.8 ml of oxalyl chloride at 0-5 C. After 2 hours, a solution of 8.61 g N,N’-dimethyl hexamethylenediamine in 25 ml of methylene chloride is added at 0 C. and the reaction mixture is stirred at room temperature for 12 hours. The insoluble salt residue is removed by filtration and methylene chloride is removed under reduced pressure. Purification by liquid chromatography affords the title compound as a thick oil.
13093-04-4, As the paragraph descriping shows that 13093-04-4 is playing an increasingly important role.
Reference£º
Patent; Ciba-Geigy Corporation; US4760179; (1988); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI