153-94-6, H-D-Trp-OH is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Synthesis of methyl esters of L- and D-tryptophanes chlorohydrates; :1a,b 2a,b a : D b : L[0344] Thionylchloride (0.064 mol) was slowly added to a cooled (O0C) suspension of tryptophane (0.049 mol) in methanol (150 mL). The reaction mixture was warmed up to 4O0C and stirred at this temperature for six hours. All solvents were removed and the solid residue was triturated with ether. The solid was filtered off to give the required product.[0345] D-tryptophane (2a): yield 98 %, M.p. 232-233C. NMR1H (delta, ppm,DMSO-dtheta, 300 MHz): 3.39 (2H, m, CH2); 3.63 (3H, s, CH3O); 4.20 (1 H1 t, CH, JHH = 5.5 Hz); 7.07 (2H, dt, Ar, JHH = 21 Hz, 6 Hz); 7.26 (1 H, d, H2, JHH = 3 Hz); 7.39 (1 H, d, Ar, JHH = 7.8 Hz); 7.53 (1 H, d, Ar, JHH = 7.8 Hz). NMR13C (delta, ppm, DMSO-d6, 125.76 MHz): 26.01 (s), 52.61 (d), 106.26(s), 111.45(s), 117.84(s), 118.50(s), 121.05(s), 124.80(s), 126.79(s), 136.13(s), 169.57(s). m/z 218(M+)., 153-94-6
153-94-6 H-D-Trp-OH 9060, acatalyst-ligand compound, is more and more widely used in various fields.
Reference£º
Patent; TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; WO2008/103470; (2008); A2;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI