With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.
General procedure: In a three-neck round bottom flask, dibenzoylmethane (0.673 g, 3 mmol)and phen (0.198 g, 1 mmol) were dissolved in hot methanol (20 mL). To the solution mixture, 3 mL o fsodium hydroxide (0.1 M) was added. The temperature of the reaction mixture was maintained at 50-60C in which then Sm(NO3)3¡¤6H2O (0.445 g, 1 mmol) in methanol (20 mL) was added dropwise with stirring for 30 min. After two hours, the reaction mixture was cooled to room temperature and the resulting precipitate was filtered using vacuum filtration, washed with distilled water and cold ethanol. The product was air dried overnight. Yield: 0.252 g, 40%., 1662-01-7
The synthetic route of 1662-01-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Saleh, Muhammad Idiris; Choo, Min Yee; Chan, Tai Wei; Razali, Mohd R; Journal of Chemical Sciences; vol. 127; 12; (2015); p. 2241 – 2249;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI