With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4411-80-7,6,6′-Dimethyl-2,2′-bipyridine,as a common compound, the synthetic route is as follows.
General procedure: To a solution of [{M(mu-Cl)(ptpy)2}2] (M=Rh, Ir) (0.15mmol) in 25mL of a mixture of CH2Cl2/MeOH/H2O (1:1:0.5) the bipyridine ligand (0.3mmol) was added and the mixture refluxed with stirring for 3h. After cooling to room temperature KPF6 (0.5mmol) was added and stirred for 20min. The solvent was removed to dryness in vacuo and the residue dissolved in dichloromethane and chromatographed on alumina with CH2Cl2/acetone (9:1) as the eluent. The resulting solution was evaporated to dryness and the residue was redissolved in 5ml of dichloromethane and the product was precipitated by slow diffusion of isohexane.
4411-80-7, The synthetic route of 4411-80-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Graf, Marion; Gothe, Yvonne; Siegmund, Daniel; Metzler-Nolte, Nils; Suenkel, Karlheinz; Inorganica Chimica Acta; vol. 471; (2018); p. 265 – 271;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI