99970-84-0, [2,2′-Bipyridine]-4,4′-dicarbaldehyde is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
99970-84-0, Dry potassium carbonate (1.7 g, 12.3 mmol) and 2.1 gtriethylphosphonoacetate were suspended in 10 cm3 of anhydrousTHF and stirred at room temperature for 15 min beforethe suspension was refluxed for 20 min. After cooling thesuspension to room temperature it was transferred into amicrowave vessel and 1.0 g (4.7 mmol) of (7) in 2 cm3 anhydrousTHF were added. The vessel was sealed and heated to110 C within 10 min using a maximum power of 1000MW.The reaction temperature then was maintained for 2 h afterwhich the vessel was allowed to cool down to room temperature.After cooling, 20 cm3 of a 10% potassium carbonatesolution was added. The mixture was extracted three timeswith ethyl acetate. The organic phase was dried over sodiumsulfate and the solvent was evaporated under reduced pressure.The remaining triethylphosphonoacetate was removedby distillation in vacuo. The crude product was purified bycolumn chromatography on silica gel using a diethyl ether:light petroleum (40-60) 1 : 1 mixture as the eluent. After thesolvent mixture was evaporated a white solid was obtainedwhich was recrystallized from ethanol/water by first dissolvingthe crude product in ethanol and then adding wateruntil the solution misted. For complete crystallization thesolution was placed in the refrigerator. Yield: 40% (0.66 g,1.88 mmol).IR (298 K) [cm-1]: 2980w, 2936vw, 1726vs, 1697vs,1584m, 1545w, 1458m, 1443m, 1377s, 1294s, 1263s, 1217vs,1063vs, 1011s, 991m, 930w, 880w, 860w, 843m, 791s, 770w,746m; MS (EI) m/z (%): 352 (10) [M+]; 323 (5) [M+-C2H5]; 308 (70) [M+-C2H5 – CH3]; 280 (100) [M+-C4H9O];261 (20) [M+-C4H11O2]; 233 (25) [M+-C6H15O2]; 208 (70)[M+-C8H18O2]; 1HNMR(CDCl3):delta ppm 1.36 (t, J = 7.07Hz, 6 H) 4.30 (q, J = 7.16 Hz, 4 H) 6.73 (s, 1 H) 6.77 (s, 1H) 7.41 (dd, J = 5.05, 1.77 Hz, 2 H) 7.73 (s, 1 H) 7.69 (s, 1H) 8.55-8.58 (m, 2 H) 8.73 (d, J = 5.05 Hz, 2 H); 13C-NMR(CDCl3):delta [ppm] = 14.2, 61.0, 119.3, 122.2, 123.1, 141.8,142.8, 150.0, 156.4, 166.1; M.p.: 139 C; elemental analysis:calc. (%) for C20H20N2O4: C 68.17, H 5.72, N 7.95; found:C 67.30, H 5.66, N 8.03.
As the paragraph descriping shows that 99970-84-0 is playing an increasingly important role.
Reference£º
Article; Heintz, Katharina; Goerls, Helmar; Imhof, Wolfgang; Journal of Chemical Sciences; vol. 130; 6; (2018);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI