Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 80875-98-5, Name is H-Oic-OH, SMILES is O=[C@@]([C@H]2N[C@@]1([H])CCCC[C@]([H])1C2)O, belongs to catalyst-ligand compound. In a document, author is Das, Kanu, introduce the new discover, Application In Synthesis of H-Oic-OH.
Phosphine-free pincer-ruthenium catalyzed biofuel production: high rates, yields and turnovers of solventless alcohol alkylation
Phosphine-free pincer-ruthenium carbonyl complexes based on bis(imino)pyridine and 2,6-bis(benzimidazole-2-yl) pyridine ligands have been synthesized. For the beta-alkylation of 1-phenyl ethanol with benzyl alcohol at 140 degrees C under solvent-free conditions, ((NNN)-N-Cy2)RuCl2(CO) (0.00025 mol%) in combination with NaOH (2.5 mol%) was highly efficient (ca. 93% yield, 372 000 TON at 12 000 TO h(-1)). These are the highest reported values hitherto for a ruthenium based catalyst. The beta-alkylation of various alcohol combinations was accomplished with ease which culminated to give 380 000 TON at 19 000 TO h(-1) for the beta-alkylation of 1-phenyl ethanol with 3-methoxy benzyl alcohol. DFT studies were complementary to mechanistic studies and indicate the beta-hydride elimination step involving the extrusion of acetophenone to be the overall RDS. While the hydrogenation step is favored for the formation of alpha-alkylated ketone, the alcoholysis step is preferred for the formation of beta-alkylated alcohol. The studies were extended for the upgradation of ethanol to biofuels. Among the pincer-ruthenium complexes based on bis(imino)pyridine, ((NNN)-N-Cy2)RuCl2(CO) provided high productivity (335 TON at 170 TO h(-1)). Sterically more open pincer-ruthenium complexes such as ((NNN)-N-Bim2)RuCl2(CO) based on the 2,6-bis(benzimidazole-2-yl) pyridine ligand demonstrated better reactivity and gave not only good ethanol conversion (ca. 58%) but also high turnovers (ca. 2100) with a good rate (ca. 710 TO h(-1)). Kinetic studies indicate first order dependence on concentration of both the catalyst and ethanol. Phosphine-free catalytic systems operating with unprecedented activity at a very low base loading to couple lower alcohols to higher alcohols of fuel and pharmaceutical importance are the salient features of this report.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 80875-98-5 is helpful to your research. Application In Synthesis of H-Oic-OH.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI