Application of 153-94-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.153-94-6, Name is H-D-Trp-OH, molecular formula is C11H12N2O2. In a Article£¬once mentioned of 153-94-6
eta5-Pentamethylcyclopentadienyliridium(III) and -rhodium(III) Labeling of Amino Acids with Aromatic Side Chains – The Importance of Relativistic Effects for the Stability of Cp*IrIII Sandwich Complexes
eta5-Pentamethylcyclopentadienyhridiurn(III) and -rhodium-(III) sandwich complexes of the type [(eta5-Cp *)M(eta6-aa)]-(CF3SO3)2 (M = Ir, Rh; 3-14) containing L-tyrosine, L-trypto-phan and L-phenylalanine derivatives (aa) can be prepared by treatment of [(eta5-Cp *)ML3] (CF3SO3)2 [L = thf, (CH3)2CO, CH3CN] with the appropriate bioligand in thf for N-protected compounds and in CF3COOH for alpha-amino acids with unprotected amino groups. Coordination to the Cp*MIII fragments stabilizes the ketonic form of the tyrosine aromatic side chains, leading to a marked enhancement in the acidity of the p-hydroxy function. The crystal structure of [Cp * Ir(ActyrOMe)] (CF3SO3)2 (3b, ActyrOMe = N-acetyltyrosine methyl ester) confirms a marked distortion towards an eta5-oxohexadienyl coordination mode as may be gauged from the tilting of the p-OH plane C13/C14/C15 by no less than theta = 12.9 from that of the remaining ring atoms. Facial isomers are present in an effective 1:1 ratio for all tryptophan derivatives. Whereas the Cp *III sandwich complexes of aromatic a-amino acids are stable in polar solvents, rapid decay is observed for analogous Cp*RhIII complexes of N-unprotected derivatives in polar solvents. Comparative nonrelativistic and relativistic all-electron density functional calculations on the cationic sandwich complexes [Cp *(eta6-C6H5Me)]n¡Â (n = 2, M = Ir, Rh; n = 1, M = Ru) confirm that all three metals bind more tightly to Cp * than to toluene as gauged by the respective force constants (k1 > k2). A much larger relativistic enhancement of k2 for M = Ir (279 vs 207 Nm-1) could be responsible for the greater stability of Cp *IrIII complexes in solution.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 153-94-6
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI