Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ category: catalyst-ligand, Which mentioned a new discovery about 102490-05-1
Asymmetric synthesis of propargylamides via 3,3?-disubstituted binaphthol-modified alkynylboronates
(Chemical Equation Presented) Alkynylboronates derived from 3,3?-disubstituted-2,2?-binaphthols react with various N-acylimines to give the expected chiral propargylamides with up to 99% ee. This new methodology was applied to the first enantioselective synthesis of the antitubulin agent (-)-N-acetylcolchinol.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, category: catalyst-ligand, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 102490-05-1
Reference£º
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI