Some tips on 137076-54-1

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137076-54-1, 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1.2 equivalents of HATU were sequentially added to the DMF solution in which the compound 6 was dissolved at 0 C, 2 equivalents of DIPEA and 0.9 equivalents of compound 7, the reaction was naturally warmed to room temperature. After completion of the reaction, it was quenched with water and extracted with ethyl acetate. The organic phase obtained by extraction was dried over anhydrous sodium sulfate and then evaporated. The residue was purified by silica gel column chromatography to give Compound 8., 137076-54-1

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Reference£º
Patent; Beijing University Shenzhen Sheng Yuan; Li Zhicheng; Ye Weijian; Huang Junrong; Liang Zhenhao; (16 pag.)CN108358952; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI