4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1,4,7-triazonane (129mg, 1.0 equiv) and K2CO3 (3.6 g, 10.0equiv) was dissolved in100 mL MeCN, a solution of 1c (1.16 g, 3.6 equiv) in 15 mL MeCNwas slowly added at 0 C, then the mixture was heated under gentlereflux for 48 h. The mixture was filtered and the filtrate concentrated invacuo and purified by flash column chromatograph on silica gel(dichloromethane /methanol as the eluent) to provide 2d light yellowsolid (545.9 mg, 64% yield). 1H NMR (400 MHz, MeOD): delta 7.54 (d,J = 7.4 Hz, 3H), 7.43 (dd, J = 7.8, 1.6 Hz, 6H), 7.34 (dd, J = 7.9,1.8 Hz, 9H), 6.43 (d, J = 7.4 Hz, 3H), 5.06 (s, 6H), 4.14 (t, J = 6.4 Hz,6H), 3.75 (t, J = 6.4 Hz, 6H), 2.67 (s, 12H), 2.25 (s, 9H). 13C NMR(101 MHz, MeOD): delta 179.2, 175.2, 147.4, 145.1, 141.4, 138.5, 130.2,129.4, 117.4, 74.6, 52.2, 38.7, 29.0, 12.8. ESI-MS: calculated forC51H60N6O6, [M+H] + m/z = 853.5, found 853.5.
The synthetic route of 4730-54-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Liu, Xiaoguang; Dong, Xiuxiu; He, Chuanchuan; Zhang, Xiaojuan; Xiang, Guangya; Ma, Xiang; Bioorganic Chemistry; vol. 96; (2020);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI