4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1.0 g (7.8 mmol) of 1,4,7-triazacyclononane and 16.7 mL of mesitylene were supplied into a 50 mL two-necked flask equipped with a reflux condenser, and 4.8 g (27 mmol) of cyclohexylmethyl bromide and 2.2 g (39 mmol) of potassium hydroxide were added. The mixture was stirred for 72 hours at 100 C. under argon gas atmosphere. After reaction completed, salt was removed by filtration, and then the filtrate was concentrated and purified by reduced-pressure distillation. (Amount of yield 2.7 g, Yield 83%) [0092] 1H-NMR(chloroform-d,ppm):0.75-1.90(m,33H), 2.23(d,6H), 2.68(s,12H) [0093] 13C-NMR(chloroform-d,ppm):26.6, 27.3, 32.3, 36.9, 57.0, 67.0 IR(KBr method, cm-1): 2919, 2849, 2788, 1448, 1357, 1314, 1263, 1161, 1113, 1033, 997, 965, 892, 843, 792, 728 [0094] Elemental analysis/calculated value: C(77.63%), H(12.31%), N(10.06%)/observed value: C(78.02%), H(12.43%), N(9.89%) [0095] (ii) Synthesis of Cu(cHexMe3tacn): [0096] To 0.36 g (0.86 mmol) of 1,4,7-tris(cyclohexylmethyl)-1,4,7-triazacyclononane, 10 mL of dichloromethane/methanol was added to obtain a uniform solution, and then 5 mL of dichloromethane/methanol containing 0.15 g (0.88 mmol) of cupric chloride dehydrate was added. The mixture was stirred for one hour at room temperature. After reaction completed, solvent was removed in vacuum, and then the residue was recrystallized from dichloromethane/methanol. (Amount of yield 0.28 g, Yield 59%) [0097] IR(KBr method, cm-1):2929, 2922, 2916, 2849, 1496, 1447, 1106, [0098] Elemental analysis/calculated value: C(58.74%), H(9.31%), N(7.61%)/observed value: C(58.35%), H(9.25%), N(7.58%)
The synthetic route of 4730-54-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Higashimura, Hideyuki; Kotake, Eiichi; Kubota, Masaaki; Kobayashi, Shiro; US2004/267057; (2004); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI