4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of a LiOEt in THF (1.0M, 2.0mL) was added dropwise to a solution of TACN (201mg, 1.56mmol) in THF (20mL), and stirred at 0C under argon. After 10min, a solution of 9 (772mg, 1.56mmol) was added dropwise at 0C, and the mixture was stirred at room temperature for 12h. The mixture was then diluted with 2¡Á50mL of ethyl acetate and dried over MgSO4. The solvent was removed under reduced pressure, and the residue was purified by flash column chromatography (Al2O3, CHCl3) to give 620mg (0.452mmol, 29%) of 10 as a white solid. 1H NMR (400MHz, CDCl3) delta (ppm): 2.76-2.79 (q, 6H); 2.83 (s, 12H); 3.12-3.14 (q, 6H); 3.53-3.56 (q, 3H); 3.57 (s, 6H); 3.61-3.75 (q, 3H); 3.83-3.85 (q, 6H); 4.35-4.38 (d, 2H); 4.47-4.59 (m, 12H); 7.21-7.32 (m, 36H). 13C NMR (100MHz, CDCl3) delta (ppm): 51.2, 52.2, 55.4, 62.7, 70.3, 73.0, 74.9, 80.6, 125.5, 126.9, 127.7, 127.8, 129.1, 136.8, 137.6, 138.5, 138.6, 140.3. ESI TOF MS: m/z [M+H]+ calcd for 1372.6832, found 1372.6834.
4730-54-5, The synthetic route of 4730-54-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Miyake, Yuka; Kimura, Yu; Orito, Naomi; Imai, Hirohiko; Matsuda, Tetsuya; Toshimitsu, Akio; Kondo, Teruyuki; Tetrahedron; vol. 71; 26-27; (2015); p. 4438 – 4444;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI