4730-54-5, 1,4,7-Triazacyclononane is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A three necked flask was charged with TACN (5.0 g, 39 mmol), followed by the additionof deoxygenated ethanol (150 mL), LiOHH2O (0.4 g, 9.5 mmol) in deoxygenated H2O (50 mL).The resulting solution was slightly cloudy and was allowed to stir at 50 C for 30 min. 4-Vinylbenzylchloride (1.1 g, 7.5 mmol) in ethanol was added dropwise to the mixture. The reaction mixture wasrefluxed under N2. After 2 h, the reaction mixture was concentrated to 50 mL on a rotary evaporator.Water was added to the residue and the solution was extracted 3-times with dichloromethane (30 mL).The combined dichloromethane extracts were washed with brine, dried with anhydrous Na2SO4,and concentrated under reduced pressure. The residue was loaded onto a silica column and elutedusing chloroform-methanol (50:50, v/v, and 1% of triethylamine). Upon removal of the solvents,the chromatographically purified N-(4-vinylbenzyl)-1,4,7-triaza-cyclononane (0.5 g) was obtainedas a light brown viscous oil and used immediately for the preparation of the grafted polystyreneparticles. Typical recovered yields of the purified N-(4-vinylbenzyl)-1,4,7-triaza-cyclononane were5%, 1H-NMR (CDCl3), delta (ppm), 2.65-3.1 (m, 12H, ring CH2) 3.68 (s, 2H, benzyl CH2), 5.18 (d, 1H,CH=CH2), 5.65 (d, 1H, CH=CH2), 6.65 (dd, 1H, CH=CH2), 7.20 (d, 2H, aromatic CH), 7.30 (d, 2H,aromatic CH), FT-IR (KBr) 3361, 2918, 2849, 1654, 1559 cm-1.
4730-54-5, The synthetic route of 4730-54-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI