5350-41-4, N,N,N-Trimethyl-1-phenylmethanaminium bromide is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: The desired amount of substrate, boronic acid (3 equiv), base (3equiv), Pd(OAc)2 (2.5 molpercent) and ligand (5 molpercent) were weighed out as solids, the vial was sealed and purged with argon, then solvent was added and the vial was purged again. The reactions were run for 14 h at the specified temperature. The crude material was filtered through a pad of Celite and washed three times with CHCl3. The solvent was removed under reduced pressure, an internal standard was added and the reaction was analysed by 1H NMR spectroscopy. For purification, the analysed mixture was concentrated, the product extracted with Et2O and filtered through anhydrous MgSO4 and further purified by flash column chromatography., 5350-41-4
The synthetic route of 5350-41-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Tuertscher, Paul L.; Davis, Holly J.; Phipps, Robert J.; Synthesis; vol. 50; 4; (2018); p. 793 – 803;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI