Lundt, Inge; Pedersen, Christian published the article 《Preparation of some 2,3-dideoxylactones by an unusual catalytic hydrogenolysis》. Keywords: hydrogenolysis bromodeoxyaldonolactone palladium; aldonolactone dideoxy.They researched the compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one( cas:32780-06-6 ).Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:32780-06-6) here.
Hydrogenolysis of 2-bromo-2-deoxyaldono-1,4-lactones in EtOH over Pd/C gave good yields of the corresponding 2,3-dideoxylactones with removal of not only the Br atom but also the C-3-OH group. For example, hydrogenolysis of bromoaldonolactone I (R = OH) in EtOH over Pd/C gave 76% dideoxyaldonolactone II (R = OH), which was also analogously obtained from bromolactone III. Similar hydrogenolysis of I (R = Br) gave 71% II (R = Br).
《Preparation of some 2,3-dideoxylactones by an unusual catalytic hydrogenolysis》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound((S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one)Name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one.
Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI