Tag: M.W:200-300

4479-74-7,4479-74-7, 2,2-Bipyridine-6,6-dicarboxylic Acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of Tb(NO3)3¡¤6H2O (0.045 g, 0.10 mmol), H2bpdc (0.024 g, 0.10 mmol) in distilled water (10 mL) that adjusted the pH value to 2.5 with 0.5 mol L-1 NaOH aqueous solution. It was then sealed in a 25 mL Teflon reactor and heated at 160 C for 72 h, and then cooled to ambient temperature at a rate of ca.2 C h-1 to give colorless block crystals of 7, yield: 57% based on H2bpdc.

The synthetic route of 4479-74-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Ya-Lan; Wang, Fei; Hu, Huai-Ming; Chang, Zhuguo; Yang, Meng-Lin; Xue, Ganglin; Inorganica Chimica Acta; vol. 434; (2015); p. 104 – 112;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.57709-61-2,1,10-Phenanthroline-2,9-dicarboxylic acid,as a common compound, the synthetic route is as follows.

57709-61-2, Dark red crystals of 2 were prepared in a similar way to 1 except forusing H2O/MeCN (10 mL, v/v=1/1) instead of MeOH. Product wasisolated in 73percent yield based on Fe. Anal. Calcd. for C32H22FeN7O8: C55.83, H 3.22, N 14.24percent Found C 54.13, H 2.88, N 12.93percent. IR (selectedbands): 3067 (m), 1638 (s), 1508 (w), 1365 (s), 1271 (s), 875(m), 812 (s), 709 (m) cm?1.

As the paragraph descriping shows that 57709-61-2 is playing an increasingly important role.

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Article; Ramezanpour, Behnaz; Mirzaei, Masoud; Jodaian, Vida; Niknam Shahrak, Mahdi; Frontera, Antonio; Molins, Elies; Inorganica Chimica Acta; vol. 484; (2019); p. 264 – 275;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

137848-29-4, (S)-2′-Amino-[1,1′-binaphthalen]-2-ol is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 0.100 g (0.351 mmol) of (S)-NOBIN and 0.115 g (0.422 mmol) of 2-benz[a]anthraldehyde-1-ol were refluxed in absolute ethanol (10 mL) under argon for 10 h producing a dark redsolution and precipitate. The mixture was hot-filtered and washed with hot ethanol to produce a dark red solid that was dried in vacuo. Yield of (S)-2: 0.591 g, 81% from (S)-NOBIN. Melting point = 209 C;[alpha]D (20 C) = +126 (c = 1.04, THF); 1HNMR (CDCl3, 400 MHz): d 4.91(s, 1H, OH); 7.31 (d, 1H, J = 3.4 Hz, CH); 7.37 (m, 4H, CH); 7.41 (d, 1H,J = 3.8 Hz, CH); 7.43 (d, 1H, J = 1.8 Hz, CH); 7.61 (m, 4H, CH); 7.71 (d,1H, J = 2.8 Hz, CH); 8.05 (m, 4H, CH); 8.20 (d, 1H, J = 3.4 Hz, CH); 8.31(s, 1H, CH); 8.34 (d, 1H, J = 3.4 Hz, CH); 8.39 (d, 1H, J = 2.2 Hz, CH);8.41 (d, 1H, J = 2.2 Hz, CH); 8.92 (s, 1H, CH); 9.96 (s, 1H, CH); 14.98(s, 1H, OH). 13C NMR (CDCl3, 100 MHz): d 116.15, 116.25, 116.86,118.03, 119.74, 123.87, 124.84, 125.66, 125.82, 126.02, 126.48,126.74, 127.04, 127.14, 127.58, 128.00, 128.63, 128.76, 128.97,129.60, 129.78, 129.95, 130.61, 131.12, 131.24, 131.31, 131.33,132.85, 133.02, 133.80, 133.89, 137.33, 143.84, 151.39, 161.18,164.04. TOF-MS (m/z): [M]+ Calcd for C39H25O2N1 540.184, found 540.115. Anal. Calc. for C39H25O2N1: C, 86.80; H, 4.67; N, 2.60. Found:C, 86.59; H, 4.51; N, 2.43%. Single crystals suitable for X-ray analysis were grown by slow diffusion of hexane into a methylene chloride solution of (S)-2., 137848-29-4

As the paragraph descriping shows that 137848-29-4 is playing an increasingly important role.

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Article; Barman, Sanmitra; Desper, John; Levy, Christopher J.; Polyhedron; vol. 84; (2014); p. 168 – 176;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.99970-84-0,[2,2′-Bipyridine]-4,4′-dicarbaldehyde,as a common compound, the synthetic route is as follows.

99970-84-0, A mixture of 4,4′-diformyl-2,2′-bipyridine (234 mg,1.10 mmol) and 5-amino-1,10-phenanthroline (669 mg,3.43 mmol) in ethanol (50 mL) was heated to 80 C for12 h, giving a suspension. The reaction mixture was filtered hot, and the solid was washed with hot ethanol, affording the desired product as a yellow solid. Yield:486 mg (78 %). ESI-MS: m/z = 567.4 (M + H)+. 1HNMR (400 MHz, CDCl3): d = 7.68 (dd, J = 8.0, 4.8 Hz,2H), 7.74 (dd, J = 8.0, 4.4 Hz, 2H), 8.07 (dd, J = 5.2,1.2 Hz, 2H), 8.29 (dd, J = 2.8, 1.6 Hz, 2H), 8.31 (dd,J = 3.2, 1.6 Hz, 2H), 8.83 (dd, J = 8.4, 1.6 Hz, 2H), 8.88(s, 2H), 8.98 (d, J = 4.8 Hz, 2H), 9.07 (s, 2H), 9.19 (dd,J = 4.4, 2.0 Hz, 2H), 9.28 (dd, J = 4.4, 2.0 Hz, 2H). IR numax (KBr, cm-1): 3417 (br), 1628m, 1597s, 1554m,1505w, 1424m, 1383s, 1297w, 1206w, 1143w, 1062m,987w, 805w, 741s, 708w, 623w, 541w. Found: C 76.0, H3.8, N 19.7; Calcd for C36H22N8: C 76.3, H 3.9, N 19.8 %.

The synthetic route of 99970-84-0 has been constantly updated, and we look forward to future research findings.

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Article; Cheng, Feixiang; Yu, Shiwen; Ren, Mingli; He, Chixian; Yin, Hongju; Transition Metal Chemistry; vol. 41; 3; (2016); p. 305 – 314;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4568-71-2,3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride,as a common compound, the synthetic route is as follows.

1-(3-Methoxy-4-propoxy-5-iodophenyl)-4-(3,4,5-trimethoxyphenyl)-1,4-butanedione (compound 126, FIG. 5) 3,4,5-Trimethoxyphenylvinylketone (11.6 g, 0.052 mol), 3-methoxy-4-propoxy-5-iodobenzaldehyde (13.8 g, 0.043 mol), and 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride (4.6 g. 0.017 mol) were stirred in trimethylamine (35 mL) at 60¡ã C. for 16 hours. The solution was then acidified, poured into chloroform (500 mL) and washed with 10percent HCl, water and saturated aqueous sodium chloride. The organic layer was dried over magnesium sulfate, concentrated under reduced pressure, and the product isolated from petroleum ether-ethyl acetate to provide pale yellow microcrystals (27 g, 92percent), m.p. 119¡ã-121¡ã C. 1 H NMR (CDCl3) 1.07 (t, 3 H), 1.86 (m, 2 H), 3.40 (dd, 4H), 3.88 (s, 3H), 3.92 (s, 9H), 4.04 (t, 2 H), 7.29 (d, 1 H), 8.07 (d, 1 H).

4568-71-2, As the paragraph descriping shows that 4568-71-2 is playing an increasingly important role.

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Patent; CytoMed, Inc.; US5358938; (1994); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

787-70-2, [1,1′-Biphenyl]-4,4′-dicarboxylic acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

787-70-2, In a typical preparation, a solid mixture of H2BPDC (H2BPDC = 4,4′-biphenyldicarboxylic acid; 0.1039 g, 0.4 mmol), bpy (bpy = 4,4′-bipyridine; 0.033 g, 0.2 mmol), and Cu(NO3)2¡¤3H2O (0.105 g, 0.4 mmol) was dissolved in a mixture of DMF (DMF = N,N’-dimethylformamide; 30 ml), pyridine (0.3 ml), and methanol (3 ml). The resulting solution was stirred at 70 C for 5 min and then distributed to four 20-ml vials. The vials were then heated at 120 C in an isothermal oven for 24 h. After cooling the vials to room temperature, the solid product was removed by decanting with mother liquor and washed in DMF (3 x 10 ml) for 3 days. Solvent exchange was carried out with methanol (3 x 10 ml) at room temperature for 3 days. The material was then evacuated under vacuum at 140 C for 6 h, yielding 0.103 g of Cu2(BPDC)2(BPY) in the form of blue crystals (67.5% based on copper nitrate).

As the paragraph descriping shows that 787-70-2 is playing an increasingly important role.

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Article; Phan, Nam T.S.; Vu, Phuong H.L.; Nguyen, Tung T.; Journal of Catalysis; vol. 306; (2013); p. 38 – 46;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

554-95-0,554-95-0, Benzene-1,3,5-tricarboxylic acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Trimesic acid (5 g, 23.8 mmol) was suspended in methanol (15 mL) and heated to reflux. When a clear solution obtained,1.6 mL of con.H2SO4 was added slowly and the mixture was refluxed for 6 h. After 3 h, white solid get precipitated from the solution. The mixture was cooled to room temperature, slowly neutralized with saturated NaHCO3 solution, filtered and washed with excess water until the aqueous layer turned neutral. It was then dried to yield a white solid of trimethyl-1,3,5-benzenetricarboxylate (5.72 g). LiAlH4 tablets (2.5 g, 66 mmol) were suspended and refluxed in dry THF (50 mL) under an inert N2 atmosphere. Trimethyl-1,3,5-benzenetricarboxylate (5 g, 20 mmol) was dissolved in 100 mL dry THF and added to the suspension in 1 h. The solution was then refluxed for 24 h, cooled to 0 C and acidified with 1MHCl. THFwas removed under reduced pressure and the aqueous suspension (100 mL) thus obtained was extracted with ethyl acetate for 48 h in a liquideliquid extractor to yield 1,3,5-trimethylolbenzene which appeared as colorless crystals in room temperature. The mother liquor was concentrated to yield second fraction. Both the fractions were NMR pure and the combined yield was 4.96 g.

The synthetic route of 554-95-0 has been constantly updated, and we look forward to future research findings.

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Article; Siyad; Kumar, G.S. Vinod; Polymer; vol. 53; 19; (2012); p. 4076 – 4090;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

14162-95-9, 4-Bromo-2,2′-bipyridine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a flame dried 50-mL 3-neck flask fitted with a condenser, a mixture of anthraceneboronic acid 35-7 (522 mg, 0.985 mmol), 4-bromo-2,2?-bipyridine (154 mg, 0.657 mmol), and cesium carbonate (640 mg, 1.97 mmol) in EtOH (15 mL) and water (2 mL) was degassed by refluxing under argon stream for 75 minutes. Then Pd(OAc)2 (29.7 mg, 0.131 mmol) and PPh3 (138 mg, 0.526 mmol) were added in one portion. Refluxing under argon was continued until the reaction was complete in 90 minutes. The reaction mixture was then allowed to cool to room temperature and filtered; the solid residue was rinsed with DCM and MeOH. The filtrate was concentrated in vacuo, and the resulting residue was purified by reversed-phase flash chromatography (C18 SiO2, eluted with gradient of 0.09% HCl in MeOH). The pure product was isolated by basification of combined and concentrated fractions with solid NaHCO3 (200 mg) followed by extraction with DCM twice. The combined DCM layers were then dried over MgSO4 and concentrated in vacuo to yield product as a yellow solid (316 mg, 50%).

14162-95-9, As the paragraph descriping shows that 14162-95-9 is playing an increasingly important role.

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Patent; Profusa, Inc.; GAMSEY, Soya; BERNAT, Viachaslau; KUTYAVIN, Alex; CLARY, Jacob William; PRADHAN, Sulolit; US2020/383; (2020); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

5350-41-4, N,N,N-Trimethyl-1-phenylmethanaminium bromide is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

5350-41-4, General procedure: Ammonium salt 6 (1 equiv.) was suspended in dry THF (0.05 M) andstirred at 40 ¡ãC. t-BuOK (4 equiv.) was added and the mixture was stirred vigorously. After 10 minutes 2 equiv. of aldehyde 2 were added and the mixture was stirred for 3 hours at 40 ¡ãC. The reaction was then quenched by addition of a half-saturated NaCl solution. After phase separation, the aqueous phase was extracted three times with DCM and the combined organic phases were dried with Na2SO4 and evaporated to dryness. Purification by columnchromatography (gradient of heptanes and EtOAc) gave the corresponding epoxides in the reported yields as a mixture of diastereomers.

5350-41-4 N,N,N-Trimethyl-1-phenylmethanaminium bromide 21449, acatalyst-ligand compound, is more and more widely used in various fields.

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Article; Roiser, Lukas; Robiette, Raphael; Waser, Mario; Synlett; vol. 27; 13; (2016); p. 1963 – 1968;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.787-70-2,[1,1′-Biphenyl]-4,4′-dicarboxylic acid,as a common compound, the synthetic route is as follows.

787-70-2, General procedure: A mixture of Eu(NO3)3¡¤6H2O (0.089 g,0.2 mmol), Na2L (0.112 g, 0.2 mmol), 1,10-phenanthroline¡¤H2O (0.04 g, 0.2 mmol), 4,4?-biphenyldicarboxylic acid (0.05 g, 0.2 mmol), one drop triethylamine and H2O(15.0 ml) in a 25 ml Teflon-lined autoclave was heated at 150 C for 33 h. After the mixture was cooled slowly to ambient temperature, yellow block crystals were obtained. The crystalswere filtered,washedwith distilledwater and dried at ambient temperature. The yield of the reaction,determined fromtheweight of the solvent-free material (0.138 g), is 71.5% based on Na2L. Anal. Calcd (%) for C47H32O8N2S2Eu: C,58.27; H, 3.33; N, 2.89. Found: C, 58.22; H, 3.42; N, 2.95. IR data (KBr pellet,upsilon/cm-1): 3062 (m), 3021 (m), 2668 (m), 2551 (m), 1685 (s), 1598 (s), 1417 (s),1252 (s), 760 (s), 607 (s). The procedure for preparing 2-4 is similar to that for 1,but the reaction temperature is 170 C rather than 150 C (see Supporting Information2).

787-70-2 [1,1′-Biphenyl]-4,4′-dicarboxylic acid 13084, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Shi, Dabin; Ren, Yanwei; Jiang, Huanfeng; Cai, Bowei; Lu, Jiaxian; Inorganic Chemistry Communications; vol. 24; (2012); p. 114 – 117,4;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI