Tag: M.W:200-300

168646-54-6, 5,6-Diamino-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: [Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to adichloromethane (DCM) solution (about 12 mL) of dap (21.4 mg,98percent, 0.100 mmol) and xantphos (59.0 mg, 98percent, 0.100 mmol) undera stream of dry argon by using Schlenk techniques at room temperatureand a vacuum-line system, then orange-red solutionwas obtained quickly and stirred for 1 h at room temperature.The above process can also be carried out in air with the existenceof oxygen. After filtration through absorbent cotton, layeringn-hexane onto the filtrate in air produced the product as orangeredcrystals in 35?44percent yield (39.1?49.3 mg).

168646-54-6, 168646-54-6 5,6-Diamino-1,10-phenanthroline 10910805, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Yao, Xi-Xi; Guo, Ya-Meng; Liu, Rong; Feng, Xiao-Yan; Li, Hao-Huai; Liu, Nian; Yang, Feng-Lei; Li, Xiu-Ling; Polyhedron; vol. 92; (2015); p. 84 – 92;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

29841-69-8, (1S,2S)-(-)-1,2-Diphenylethylenediamine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

3-Chloro-propanoic acid (4.34 g, 0.04 mol) was dissolved in 5.0 mL of water on ice bath and carefully neutralized with cold water solution of 5.0 mL NaOH (1.60 g, 0.04 mol). Meso-1,2-diphenyl-ethylenediamine (4.24 g, 0.02 mol) was added to this solution. The mixture was being stirred for 4 h at 90 C, and during this period 5.0 mL NaOH water soltion (1.60 g, 0.04 mol) was introduced. After that, 5.6 mL 6 mol/L HCl was added and resulting solution was evaporated to the volume of 7.0 mL; 6.0 mL conc. HCl, 6.0 mL of ethanol and 6.0 mL of ether were added to the mixture. The white precipitate of meso-1,2-diphenyl-ethylenediamine-N,N’-di-3-propanoic acid dihydrochloride monohydrate, H2-1,2-dpheddp 2HCl H2O was separated by filtration and refined with solution water: ethanol = 1: 2. Yield: 4.00 g (44.69%). Anal. Calcd. for H2-1,2-dpheddp*2HCl*H2O = C20H28Cl2N2O5 (Mr = 447.344): C, 53.69; H, 6.31; N, 6.26. Found: C, 53.88; H, 6.70; N, 6.08.

29841-69-8, 29841-69-8 (1S,2S)-(-)-1,2-Diphenylethylenediamine 6931238, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Radi?, Gordana P.; Glodovi?, Verica V.; Ratkovi?, Zoran R.; Novakovi?, Sladana B.; Garcia-Granda, Santiago; Roces, Laura; Menendez-Taboada, Laura; Radojevi?, Ivana D.; Stefanovi?, Olgica D.; ?omi?, Ljiljana R.; Trifunovi?, Sre?ko R.; Journal of Molecular Structure; vol. 1029; (2012); p. 180 – 186;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

103946-54-9, 4′-Methyl-[2,2′-bipyridine]-4-carboxylic acid is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Bis-2,2′-bipyridine ruthenium dichloride (55 mg, 0.11 mmol) Methyl-2,2′-bipyridine-4-carboxylic acid (21 mg, 0.11 mmol) were protected from light in the presence of ethanol (10 mL, 50%) under argon for 5 hours. The reaction mixture was evaporated and the residue was dissolved in 1 mL CH3CN, Add 2 mL of saturated n-butylamine in acetone. The resulting precipitate was filtered, Washed with acetone, And vacuum dried, This gave 79 mg (85%) of Ru-CO2H as a red-orange powder. (Synthesis route shown in Figure 4)., 103946-54-9

103946-54-9 4′-Methyl-[2,2′-bipyridine]-4-carboxylic acid 11127621, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Capital Medical University; Li, Minna; Peng, Shiqi; Zhao, Ming; (10 pag.)CN106146565; (2016); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

485-71-2, Cinchonidine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

4-Hydroxyphenylacetic acid(40 mg, 0.263 mmol) and cinchonidine (77.4 mg, 0.263 mmol) were both dissolved in ethyl methyl ketone. Crystals were obtained afterone week.

485-71-2, 485-71-2 Cinchonidine 101744, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Amombo Noa, Francoise M.; Jacobs, Ayesha; Journal of Molecular Structure; vol. 1114; (2016); p. 30 – 37;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.103946-54-9,4′-Methyl-[2,2′-bipyridine]-4-carboxylic acid,as a common compound, the synthetic route is as follows.

As shown in Figure 1, 4′-methyl-[2,2’dipyridyl]-4-carboxylic acid (0.3 g, 1.4 mmol) (purchased from Zhengzhou Alpha) and N-hydroxysuccinimide (NHS, 0.257 g, 2.24 mmol) were used and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC, 0.322 g, 1.68 mmol) was dispersed in a 15 mL DMF (N,N-dimethylformamide) port flask , Heat to 50 C, reaction for 12h. After the reaction was completed, the DMF solution was decontaminated under reduced pressure. Deionized water (50 mL) was added and solids precipitated.Dichloromethane extraction (15 mL, extraction 3 times) takes a light yellow organic layer. Then dry with anhydrous sodium sulfate.Take the filtrate, take the filtrate, and evaporate the filtrate with a rotary evaporator.A pale white solid is obtained, which is the active ester of dipyridylcarboxyl: 2,5-dicarbonyl-1-pyrrolidinyl 4′-methyl-[2,2′-bipyridine]-4-carboxylate (product 1), yield 65.2%., 103946-54-9

103946-54-9 4′-Methyl-[2,2′-bipyridine]-4-carboxylic acid 11127621, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Jinan University; Guangzhou Medicine Jianyansuo; Chen Tianfeng; Tian Yiqiao; Du Biying; Huang Yanyu; Gao Pan; (22 pag.)CN107573384; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.66127-01-3,3-Bromo-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

66127-01-3, Synthesis of 3-(2-ferrocenylethynyl)-1,10-phenanthroline (L2): A mixture of 3-bromo-1,10-phenanthroline (120 mg, 0.46 mmol), ethynylferrocene (80 mg, 0.38 mmol), (PPh3)2PdCl2 (10 mg), CuI (8 mg) and Et3N (1 mL) in benzene (30 mL) and methanol (5 mL) was heated to reflux for 12 h under nitrogen atmosphere. Then the solvent was evaporated under reduced pressure, the residue was purified by column chromatography on silica, being eluted with CHCl3 to afford the desired product as an orange solid. Yield: 98 mg (66 %). 1H NMR (400 MHz, CDCl3): delta = 4.31 (s, 5H), 4.33 (s, 2H), 4.60 (s, 2H), 7.67 (t, J = 11.4 Hz, 1H), 7.69-7.86 (m, 2H), 8.26 (d, J = 6.8 Hz, 1H), 8.34 (s, 1H), 9.22 (d, J = 11.2 Hz,2H). ESI-HRMS: m/z 388.0657 (M+).

The synthetic route of 66127-01-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ren, Mingli; Cheng, Feixiang; Asian Journal of Chemistry; vol. 27; 7; (2015); p. 2555 – 2558;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

485-71-2, Cinchonidine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of (-)-cinchonidine (1.0 mmol) and benzyl bromide 3 (1.0 mmol) having sulfonamidegroup was stirred in DMF (4 mL) at 25 C for 20 h. After the reaction was completed, the reaction mixture was added dropwise to ether (50mL) with stirring. The solid precipitated was filtered,washed with ether (20 mL) and hexane (20 mL) to afford cinchonidinium salt 5

485-71-2, 485-71-2 Cinchonidine 101744, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Itsuno, Shinichi; Yamamoto, Shunya; Takata, Shohei; Tetrahedron Letters; vol. 55; 44; (2014); p. 6117 – 6120;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2304-30-5,Tetrabutylphosphonium chloride,as a common compound, the synthetic route is as follows.

EXAMPLE 4 27.35 g of 3-methyl-3-chloro-2-(2′,2′-dichlorovinyl)-butanecarboxylic acid ethyl ester in the form of the crude solution prepared in Example 1 were dissolved in 50 ml of toluene. 2 g of tetrabutylphosphonium chloride were added and 16.8 g of 50% strength potassium hydroxide solution were then added dropwise at 0 C. The solution was subsequently stirred until it had reached room temperature and was then stirred for a further 1 hour at 35 C. It was then diluted with ice-water and rendered neutral and the organic phase was separated off and fractionated. This gave 21.9 g (92.5% of theory) of 2,2-dimethyl-3-(2′,2′-dichlorovinyl)-cyclopropanecarboxylic acid ethyl ester., 2304-30-5

2304-30-5 Tetrabutylphosphonium chloride 75311, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Bayer Aktiengesellschaft; US4217300; (1980); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.134030-21-0,N1,N2-Dimesitylethane-1,2-diamine,as a common compound, the synthetic route is as follows.

In a GPC bottle, N,N?- dimesityl-ethanediamine (2 mmol) and C6F5CHO (3 mmol) were introduced. The mixture was crushed with a glass rod and a few drops of glacial acetic acid were added while stirring. After adding glacial acetic acid (1 mL) a precipitate was formed. Another glacial acetic acid (1 mL) was added, and the precipitate obtained after filtration was washed with cold isopropanol (-20 C) and then dried. The product was obtained as a white powder. Yield: 0.34g, 35%. 1H NMR (250 MHz, CDCl3) delta 6.79 (s, 4H), 6.37 (s, 1H), 3.89 (m, 2H), 3.51 (m, 2H), 2.51 (s, 9H), 2.20 (s, 9H) . 13C NMR (250 MHz, CDCl3) delta 139.07, 135.46, 130.12, 71.56, 51.04, 20.71., 134030-21-0

The synthetic route of 134030-21-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Musengimana, Eric; Fatakanwa, Claver; Oriental Journal of Chemistry; vol. 29; 4; (2013); p. 1489 – 1496;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

787-70-2,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.787-70-2,[1,1′-Biphenyl]-4,4′-dicarboxylic acid,as a common compound, the synthetic route is as follows.

A mixture of Co(OAc)2*4H2O (49.2 mg, 0.2 mmol), L1 (32.3 mg, 0.1 mmol), H2bpdc (48.4 mg, 0.2 mmol), NaOH (8.0 mg, 0.2 mmol), ethanol (4 mL) and water (10 mL) was heated at 140 C for 3 days in a 25 mL Teflon-lined vessel container. The mixture was then cooled to room temperature at a rate of 5 C/h. Purple crystals suitable for single-crystal X-ray diffraction were obtained by filtration and washed with distilled water in 58 % yield (based on Co(OAc)2*4H2O). Calcd. for C34H30CoN4O4 (Fw = 617.55): C 66.1, H 4.9, N 9.1 %. Found: C 65.9, H 5.1, N 9.3 %. IR (KBr, cm-1): 1605 s, 1560 m, 1510 m, 1430 m, 1300 m, 1178 w, 847 w, 758 m.

The synthetic route of 787-70-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Zhang, Xu; Liu, Yong Guang; Yu, Baoyi; Cui, Guang Hua; Transition Metal Chemistry; vol. 41; 2; (2016); p. 213 – 223;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI