Tag: M.W:300-400

1067-33-0, Dibutyltin diacetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 1; 240 g of di-n-butyl tin diacetate (Aldrich Corp., USA) and 692 g of the bis(3-methylbutyl) carbonate produced in step (A-2) of Reference Example 1 were placed in a 2 L volumetric eggplant-shaped flask in a nitrogen atmosphere at atmospheric pressure, and a Dimroth condenser and three-way valve were attached to the flask. The flask was immersed in an oil bath heated to 150 C. and heated for 5 hours while stirring the contents. The flask was attached to a rotary evaporator to which was connected an oil bath equipped with a temperature controller, a vacuum pump and a vacuum controller. The purge valve outlet of the rotary evaporator was connected to a line containing nitrogen gas flowing at atmospheric pressure. After replacing the inside of the system with nitrogen, the temperature of the oil bath was set to be 150 C., the flask was immersed in the oil bath and rotation of the rotary evaporator was started. A low boiling point component was distilled off for about 7 hours in the presence of nitrogen at atmospheric pressure with the purge valve of the rotary evaporator left open, after which the pressure in the system was gradually reduced, and residual low boiling point component was distilled off with the pressure inside the system at 76 to 10 kPa. When the low boiling point component fraction no longer appeared, the flask was removed from the oil bath and allowed to cool. 287 g of residual liquid were obtained in the flask. Based on the results of 1H-, 13C- and 119Sn-NMR analyses, the residual liquid in the flask was a solution containing 92.0% by weight of di-n-butyl-bis(3-methylbutyloxy) tin.On the other hand, 598 g of low boiling point component were recovered. When analyzed by gas chromatography, the low boiling point component contained about 28% by weight of isoamyl acetate.

1067-33-0, As the paragraph descriping shows that 1067-33-0 is playing an increasingly important role.

Reference£º
Patent; Shinohata, Masaaki; Miyake, Nobuhisa; US2010/292496; (2010); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

39069-02-8, 2,9-Dibromo-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

31.9 g (0.101 mol) of intermediate 233-3 was dissolved in 320 ml of toluene solvent.Stir under nitrogen,16 g (0.0505 mol) of 2,9-dibromo-phenanthroline 19.6 g (0.202 mol) was added in sequence.Sodium tert-butoxide, 0.45 g (0.000505 mol) (DBA) 3Pd21.01 ml (0.000505 mol) of tri-tert-butylphosphine, heated to reflux.After 6 hours of reaction, the reaction was completed, the reaction was stopped, and the reaction solution was dried under reduced pressure.The residue obtained was recrystallized from xylene to give 20.3 g of Compound 233 (yield 52%)., 39069-02-8

39069-02-8 2,9-Dibromo-1,10-phenanthroline 15448099, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Beijing Lv Ren Science And Technology Co., Ltd.; Lv Yao; Feng Yu; Jia Xueyi; (53 pag.)CN108659010; (2018); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: A solution of [Rh2Cl2(COD)2] (0.1mmol), 1,10-phenanthroline (0.2mmol) and HBF4 (0.025ml, 40% water solution) in 5mL of ethanol was stirred at room temperature for 18h. The red-orange product was filtrated off, washed with ethanol and dried under vacuum., 1662-01-7

1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; ?liwi?ska-Hill, Urszula; Pruchnik, Florian P.; Latocha, Ma?gorzata; Nawrocka-Musia?, Dominika; U?aszewski, Stanis?aw; Inorganica Chimica Acta; vol. 400; (2013); p. 26 – 31;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

23616-79-7, N-Benzyl-N,N-dibutylbutan-1-aminium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

23616-79-7, REFERENCE EXAMPLE 5 To a mixture of 4-[4-[(5-methyl-2-phenyl-4-thiazolyl)methoxy]phenyl]butylaldehyde (4.68 g), benzyl tributylammonium chloride (2.07 g), ethyl acetate (150 mL) and water (30 mL) was added sodium cyanide (650 mg) at room temperature. After stirring for 1.5 hr at room temperature, 2N hydrochloric acid (10 mL) was added to the reaction mixture to make the mixture acidic. The ethyl acetate layer was separated, washed successively with water (80 mL) and saturated brine (50 mL) and dried (MgSO4). The solvent was evaporated under reduced pressure, and the residue was subjected to silica gel column chromatography and eluted with hexane-ethyl acetate (2:1, v/v) to give 2-hydroxy-5-[4-[(5-methyl-2-phenyl-4-thiazolyl)methoxy]phenyl]pentanenitrile (4.22 g, 84%). Recrystallization from ethyl acetate-hexane gave a colorless prism crystal. melting point: 101-102 C.

As the paragraph descriping shows that 23616-79-7 is playing an increasingly important role.

Reference£º
Patent; Hazama, Masatoshi; Miyazaki, Takeshi; Sugiyama, Yasuo; US2003/134884; (2003); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

10534-59-5, Tetrabutylammonium acetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The solution containing the sulfate (X) was re-cooled to 0 C. and a solution of Tetra butyl ammonium acetate (9 gm, 0.0301 mol dissolved in 30 ml water) was added to it. The reaction mixture was allowed to warm to 25 C. and stirred for 1 hour. The volatiles were removed under reduced pressure and residue was co-evaporated with 2¡Á50 ml Xylene to remove traces of N,N?-Dimethyl formamide. The residue was partitioned between a 1:1 mixture of water and dichloromethane (120 ml). The aqueous layer was re-extracted with dichloromethane (30 ml). The combined organic extracts were washed with water (2¡Á30 ml), brine (30 ml). And dried over Na2SO4 and the solvent evaporated under reduced pressure to obtain the crude TBA sulfate (5.2 gm). Crude compound was triturated with hexane (2¡Á30 ml) & dried on rotavapor under 4 mmHg pressure to obtain the TBA salt (XI), 5.0 g, yield-44%. [0109] Mass: 246 ((M-H)) of sulfate M.W: 488, M.F: C23H44N4O5S., 10534-59-5

10534-59-5 Tetrabutylammonium acetate 82707, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Patil, Vijaykumar Jagdishwar; Tadiparthi, Ravikumar; Birajdar, Satish; Bhagwat, Sachin; US2014/88070; (2014); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

112881-51-3, 4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of NiCl2¡¤6H2O (24mg, 0.10mmol) and pytpy (62mg, 0.20mmol) was dissolved in water (5mL) and then was stirred for 10min in air. The reaction mixture was then transferred into a 23mL Teflon-lined reactor and kept at 200C for 72h and after that it was cooled to room temperature at the rate of 10 Ch-1. The red crystals were obtained after washing with distilled water and drying in air. Yield: 74%; m.p. 344-346C (dec.). Anal. Calc. for C40H28Cl2N8Ni. 4H2O: C, 58.42; H, 4.41; N, 13.63. Found: C, 58.03; H, 4.08; N, 13.77. IR data (KBr, cm-1): 3404, 3015, 2916, 2849, 2352, 1670, 1603, 1537, 1469, 1402, 1249, 1159, 1016, 914, 793, 741, 634, 495. TGA: calc. by formula C40H28N8NiCl2. 1.5H2O: 1.5H2O %=3.48, 2 pyridine and 1 Cl %=25.89, 1Cl %=6.40, 0.5 pyridine %=7.62, 0.5 terpyridine and 0.5 pyridine %=32.57. determined: 1.5H2O %=3.37, 2 pyridine and 1 Cl %=27.18, 1 Cl %=5.35, 0.5 pyridine %=8.94, 0.5 terpyridine and 0.5 pyridine %=35.30.

112881-51-3, 112881-51-3 4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine 11438308, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Momeni, Badri Z.; Rahimi, Farzaneh; Jebraeil, S. Mohammad; Janczak, Jan; Journal of Molecular Structure; vol. 1150; (2017); p. 196 – 205;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4733-39-5,2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: 1a-j were prepared photolytically using a procedure adapted from the literature;[25] the synthesis of 1j is presented below and typifies all such syntheses performed in this work. W(CO)6(0.550 g, 1.56 mmol) was dissolved in 50mL dry tetrahydrofuran(Pharmco) and degassed in a round-bottom flask. The resulting solution was illuminated with a 100-W mercury arc lamp until nearly complete conversion to W(CO)5(THF) had been effected[26] as determined by infrared spectroscopy; this normally required 3 to 4 h of constant illumination. To the resulting yellowish-green solution was added a slight molar excess of dmp (0.347 g, 1.64 mmol) under constant stirring and nitrogen purging; this resulted in a rapid colour change and eventual precipitation of the desired product. After 30 min, the precipitate was isolated and washed with additional THF; the crude product was purified by recrystallization from dichloromethane/hexanes. The product (0.516 g, 1.02 mmol, 65%yield) consisted of brick-red crystals and its identity was confirmed by IR spectroscopy. Most of the compounds synthesized exhibited deep-red luminescence as solids.

4733-39-5, The synthetic route of 4733-39-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Bullock, John P.; Lee, Chong-Yong; Hagan, Brian; Madhani, Humair; Ulrich, John; Australian Journal of Chemistry; vol. 70; 9; (2017); p. 1006 – 1015;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4733-39-5,2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.,4733-39-5

(1) Synthesis of 2,9-bis(tosylaminomethyl)-4,7-diphenyl-1,10-phenanthroline (x) 2,9-Bis(aminomethyl)-4,7-diphenyl-1,10-phenanthroline perchlorate (w) (2.36 g, 4 mmol), which was synthesised from 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline according to the method described in J. Heterocyclic Chem., 18, 599 (1981), was dissolved in pyridine (20 ml). p-Toluene sulfonyl chloride (1.6 g, 8 mmol) was added to the solution with cooling using an ice bath, and the reaction mixture was stirred at room temperature for 3 hours. The resulting solution was poured into water (200 ml) and extracted with chloroform (200 ml). The chloroform layer was chromatographed on a silica gel column using chloroform/methanol as eluent to give the desired 2,9-bis(tosylaminomethyl)-4,7-diphenyl-1,10-phenanthroline (x) (yield=1.54 g).

4733-39-5 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline 65149, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Dojindo Laboratories; Mochida Pharmaceutical Co., Ltd.; US5262526; (1993); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.144222-34-4,N-((1R,2R)-2-Amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide,as a common compound, the synthetic route is as follows.

Step 5: Preparation of catalyst 14; The catalyst was prepared by mixing lmol equiv of [RuCl2(p-cymene)2], 2mol equiv(R,R)-N-Tosyl-l,2-diphenylethylene-l,2-diamine and 4.2 mol equiv OfEt3N in iPrOH at 80 0C for Ih. After solvent removal, the solid was washed with cold H2O and the recrystallized from MeOH to give the catalyst as an orange solid., 144222-34-4

144222-34-4 N-((1R,2R)-2-Amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide 2734565, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; MERCK FROSST CANADA LTD.; WO2007/14454; (2007); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

115754-62-6, ((1,3-Dioxolan-2-yl)methyl)tributylphosphonium bromide is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,115754-62-6

General procedure: The compounds 4ab were synthesized via modified literature procedure [34]. Aldehyde 3a or 3b (2 mmol) and tributyl(1,3- dioxolan-2-ylmethyl)phosphonium bromide (1.63 g, 4.4 mmol) were dissolved in dry THF (50 mL). Argon was bubbled through the solution for 15 min, NaH (144 mg, 6 mmol) was added and the reaction mixture was stirred at room temperature for 24 h. The reaction mixture was diluted with water (100 mL) and extracted with EtOAc (3 100 mL). The combined organic layers were dried (Na2SO4) and the solvents were evaporated in vacuo. The residue was dissolved in THF (100 mL), 12% HCl (50 mL) was added and the solution was stirred for 1 h. The reaction mixture was diluted with water (100 mL) and extracted with EtOAc (3 100 mL). Both products 4a and 4b are sparingly soluble in common organic solvents. Therefore, the collected organic suspensions was concentrated in vacuo and precipitate was filtered off. The crude product 4a or 4b was suspended in EtOAc (50 mL), the suspension was refluxed for 30 min, cooled to 25 C and the product was isolated by filtration. After drying, products 4a and 4b were used in the following reaction step without further purification. A full purification of small quantities is possible by column chromatography (SiO2, CH2Cl2/EtOAc 10:1) using large excess of the eluting solvents.

115754-62-6 ((1,3-Dioxolan-2-yl)methyl)tributylphosphonium bromide 22292430, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Speratova, Michaela; Jedyrka, Jaroslaw; Pytela, Old?ich; Kityk, Iwan V.; Reshak; Bure?; Klikar; Tetrahedron; vol. 75; 34; (2019);,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI