Tag: M.W:300-400

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7173-51-5,N-Decyl-N,N-dimethyldecan-1-aminium chloride,as a common compound, the synthetic route is as follows.

7173-51-5, EXAMPLE 3 Preparation of 2,6-dinitro-3,4-dimethyl anisole A solution of 226 g 2,6-dinitro-3,4-xylenol, 93.7%. (1 mole) in two liters 1,2-dichloroethane was placed in a three liter reaction flask. Sodium carbonate 128 g (1.2 moles) and 0.81 g Didecyldimethyl-ammonium chloride (DDAC) were added to the above solution and afterwards 151.3 (1.2 moles) of dimethylsulfate were introduced during 15 minutes at the ambient temperature. The reaction mixture was heated with stirring to reflux during two hours. Water (400 ml) was added and heating was continued for another hour. This mixture was cooled to 25 C. and allowed to separate in two phases. The lower organic phase was separated, washed with water to neutral. The solvent was next recovered by distillation and the remaining oily produce solidified by cooling. A product (225.8 g) of 94%. 2,6-dinitro-3,4-dimethylanisole was obtained at a 93.9% of the theoretical yield based on 2,6-dinitro-3,4-xylenol consumed.

As the paragraph descriping shows that 7173-51-5 is playing an increasingly important role.

Reference£º
Patent; Agan Chemical Manufacturers Ltd.; US5475148; (1995); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

13104-56-8, 4′-(4-Methoxyphenyl)-2,2′:6′,2”-terpyridine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Methanolic solution of CuCl2¡¤2H2O (1.5 mmol) was added to a methanolic solution of 4?-(3-chlorophenyl)-2,2?:6?,2?-terpyridine (L1) (1.5 mmol), followed by the addition of a previously prepared methanolic solution of sparfloxacin (1.5 mmol) in presence of CH3ONa (1.5 mmol). The pH of the reaction mixture was adjusted to ~6.8. The resulting solution was refluxed for 2 h. on a water bath, followed by concentrating to half of its volume. A fine, green amorphous product obtained was washed with ether/hexane and dried in a vacuum desiccator. The proposed reaction scheme for the synthesis of complex has been kept in the Supplementary Material.

13104-56-8, As the paragraph descriping shows that 13104-56-8 is playing an increasingly important role.

Reference£º
Article; Patel, Mohan N.; Joshi, Hardik N.; Patel, Chintan R.; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 104; (2013); p. 48 – 55;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

10534-59-5, Tetrabutylammonium acetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Preparation of four different solutions of tetradecavanadates, VxOyALz (A = Cl- or CH3CO2-, L = (C2H5)4N+ or (C4H9)4N+), was carried out according to a modified literature procedure [31]. All chemicals were purchased from Sigma-Aldrich and used as received. Briefly, 1.5 mmol of vanadyl acetylacetonate [VO(acac)2] and 0.6 mmol of either tetraethylammonium chloride [(C2H5)4NCl], tetrabutylammonium chloride [(C4H9)4NCl], tetraethylammonium acetate [(C2H5)4N(CH3CO2)] or tetrabutylammonium acetate [(C4H9)4N(CH3CO2)] were dissolved in 50 mL of acetonitrile. 0.8 mmol of triethyl amine was then added to the initial mixtures while stirring constantly at room temperature. Following 6 h of reaction, an Oakton 10 series pH meter (calibrated using buffers of pH 4, 7 and 10 at room temperature) was used to determine the pH of the resulting brown-colored solutions. The product mixtures were de-solvated under reduced pressure using a VWR1400E vacuum oven. Recrystallization was carried out in approximately 3 mL of N,N-dimethylformamide (N,N-DMF) by heating the solution to the boiling temperature (153 C) for 10 min. Any remaining N,N-DMF was then evaporated in vacuum to obtain pure dry crystals of polyoxovanadates. A small quantity of crystals was dissolved in acetonitrile to prepare concentrated stock solutions. These stock solutions were diluted further by factors of ten or one hundred in acetonitrile prior to analysis by ESI-MS.

10534-59-5, The synthetic route of 10534-59-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Johnson, Grant E.; Al Hasan, Naila M.; Laskin, Julia; International Journal of Mass Spectrometry; vol. 354-355; (2013); p. 333 – 341;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

[CuI(MeCN)4](ClO4) (50mg, 0.15mmol), PPh3 (80.4mg, 0.30mmol) and Ph2Phen (55.9mg, 0.17mmol) in MeCN (15ml) are stirred at room temperature for 1h. Slow evaporation of a MeCN solution of 3 afforded analytically pure complex as yellow crystalline solid. Yield (93.1mg, 59.8%). Elemental analysis for C60H46ClCuN2O4P2: calcd. C 70.65, H 4.55, N 2.75%; found: C 70.60, H 4.70, N 2.77%. Selected IR (KBr, cm-1): v(Cl-O) 1111. ESI-MS (positive): m/z 919 (M+). 1H NMR (300MHz, CDCl3): delta 8.83 (d, J=5.0Hz, 2H, phen H); 8.01 (s, 2H, phen H); 7.74 (d, J=5.0Hz, 2H, phen H); 7.62 (m, 6H, phenyl H); 7.57-7.51 (m, 4H, phenyl H); 7.37 (m, 6H, phenyl H); 7.26-7.14 (m, 24H, phenyl H). 31P{1H} NMR (162MHz, CDCl3): delta 2.97 (s, PPh3). UV/Vis (CH3CN): lambdamax /nm (epsilon/mol-1dm3cm-1): 228 (71180), 285 (58210), 381 sh (5810).

1662-01-7, As the paragraph descriping shows that 1662-01-7 is playing an increasingly important role.

Reference£º
Article; Hu, Lin-Li; Shen, Chang; Chu, Wing-Kin; Xiang, Jing; Yu, Fei; Xiang, Ge; Nie, Yan; Kwok, Chun-Leung; Leung, Chi-Fai; Ko, Chi-Chiu; Polyhedron; vol. 127; (2017); p. 203 – 211;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

139-07-1, N-Benzyl-N,N-dimethyldodecan-1-aminium chloride is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The API-IL benzalkonium salicylate was prepared from benzyldimethyldodecylammoniumchloride (benzalkonium chloride) and sodium salicylate according to a procedure similar tothat described in the literature [8]. Sodium salicylate (0.93 g, 5.8 mmol) and benzyldimethyldodecylammoniumchloride (2.05 g, 5.8 mmol) were dissolved in 20 mL of acetone/H2O(1:1). The reaction mixture was stirred overnight at room temperature. The remaining suspensionwas diluted with 20 mL of distilled water. The product was extracted with dichloromethane.Sodium chloride as a byproduct was removed by washing the dichloromethane phase successivelywith water. The presence of chloride ions in the washings was detected using AgNO3solution. The dichloromethane was evaporated under reduced pressure. The obtained API-ILwas further dried at 343 K in vacuum for 8 h. The water content of the API-IL was determinedby a Karl-Fischer measurement, and the value was about 350 ppm. The synthesized API-ILwas characterized by 1H NMR (Bruker DPX) and IR (Nicolet IR-470).The characterization values obtained are: IR (KBr, cm-1): 3437(s), 3027(w), 2921(s),2852(s), 1638(s), 1590(s), 1484(s), 1456(s), 1219(s), 1137(m), 758(m), 735(m);1H NMR:(400 MHz, CDCl3)delta in ppm: delta 7.97 (dd, J = 7.7, 1.7 Hz, 1H), 7.48 (m, 6H), 6.87 (d,J = 8.2 Hz, 1H), 6.76 (t, J = 7.4 Hz, 1H), 4.82 (s, 2H), 3.36 (m, 2H), 3.21 (s, 6H), 1.74 (s, 2H),1.24 (d, J = 7.4 Hz, 18H), 0.88 (t, J = 6.8 Hz, 3H). The 1H NMR spectra of BaSal is presentedin Fig. S1 of the Supplementary Material.Thermal stability was measured on a STA 409 PC simultaneous thermal analyzer (Germany)in the range of 303-773 K at a heating rate of 10 K¡¤min-1 under an air environment. Itcan be seen from Supplementary Fig. S2 that BaSal has good thermal stability with the lowdecomposition temperature of 454 K., 139-07-1

The synthetic route of 139-07-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yan, Zhenning; Shen, Shuangxia; Ma, Limin; Liu, Liyun; Chen, Xue; Journal of Solution Chemistry; vol. 47; 9; (2018); p. 1514 – 1528;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1435-55-8, Hydroquinidine is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

From dihydroquinidine To a 0 C. solution of 1.22g dihydroquinidine (0.0037 mol) in 30mL of CH2 Cl2 was added 0.78mL of Et3 N (0.0056 mol; 1.5 eq), followed by 0.71mL of p-chlorobenzoyl chloride (0.005 mol; 2 eq) in 1mL CH2 Cl2 After stirring 30 minutes at 0 C. and 1 hour at room temperature, the reaction was quenched by the addition of 10% Na2 CO3 (20mL). After separation, the aqueous layer was extracted with three 10mL portions of CH2 Cl2. The combined organic layers were dried over Na2 S04 and the solvent removed under vacuum. The crude product was purified as described above. Dihydroquinidine p-chlorobenzoate (1) was obtained in 91% yield (1.5g) as a white foam.

1435-55-8, 1435-55-8 Hydroquinidine 16401293, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Massachusetts Institute of Technology; US4965364; (1990); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

1067-33-0, Dibutyltin diacetate is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 7; 306 g of a residual liquid were obtained by carrying out the same method as Example 6 with the exception of using 255 g of di-n-butyl tin diacetate, and using 961 g of 3-methyl-1-butanol (Tokyo Chemical Industry Co., Ltd., Japan) instead of 2-ethyl-1-butanol. The residual liquid contained 92.7% by weight of di-n-butyl-bis(3-methylbutyloxy) tin. In addition, the low boiling point component contained 18.0% by weight of isoamyl acetate.

1067-33-0, 1067-33-0 Dibutyltin diacetate 16682740, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Shinohata, Masaaki; Miyake, Nobuhisa; US2010/292496; (2010); A1;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1662-01-7,4,7-Diphenyl-1,10-phenanthroline,as a common compound, the synthetic route is as follows.

General procedure: The corresponding ligand (1mmol) was added to a MeCN solution (40mL) of the corresponding metal pivalate (1mmol). The resulting mixture was stirred at t=60C for 2h, filtered off, and slowly cooled to room temperature. The solution was kept at room temperature, and crystals precipitated for 6-48h. In some cases, single crystals suitable for X-ray diffraction studies were obtained after recrystallisation from MeCN (slow evaporation under reduced pressure).

1662-01-7, 1662-01-7 4,7-Diphenyl-1,10-phenanthroline 72812, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Article; Nikolaevskii, Stanislav A.; Evstifeev, Igor S.; Kiskin, Mikhail A.; Starikova, Alyona A.; Goloveshkin, Alexander S.; Novikov, Valentin V.; Gogoleva, Natalya V.; Sidorov, Alexey A.; Eremenko, Igor L.; Polyhedron; vol. 152; (2018); p. 61 – 72;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

156492-30-7, 4,7-Dibromo-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The compound 73d (5.1 g, 15.0 mmol),Phenoxazine (5.8 g, 32 mmol)Tert-butylphosphine (0.35 g, 2 mmol),Palladium acetate (0.4 g, 1.8 mmol) and cesium carbonate (19.5 g, 60 mmol) were dissolved in toluene,Under a nitrogen atmosphere,The reaction was heated under reflux for 10 hours.The solvent was evaporated in vacuo,The remaining material was stirred with pentane,filter,Purification by silica gel column chromatography,To obtain solid compound 5, (5.31 g, 9.8 mmol)Yield 65%.

156492-30-7, 156492-30-7 4,7-Dibromo-1,10-phenanthroline 11393583, acatalyst-ligand compound, is more and more widely used in various fields.

Reference£º
Patent; Shanghai Tianma Organic Shine Display Co., Ltd.; Tianmawei Electronic Co., Ltd.; Wang Xiangcheng; Liu Ying; Ren Hongyang; He Wei; Liu Chen; (43 pag.)CN106831743; (2017); A;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI

100125-12-0, 3,8-Dibromo-1,10-phenanthroline is a catalyst-ligand compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: [Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to a dichloromethane (DCM) solution (about 10 mL) of BrphenBr (33.6 mg, 0.100 mmol) and BINAP (63.5 mg, 98%, 0.100 mmol) under a stream of dry argon using Schlenk techniques at room temperature. After stirring for 5 h at room temperature, n-hexane was carefully dropped over the DCM solution, and orange-yellow crystals were obtained a few days later in 52.5% yield (67.9 mg)., 100125-12-0

The synthetic route of 100125-12-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Feng, Xiao-Yan; Xin, Xue-Lian; Guo, Ya-Meng; Chen, Ling-Ling; Liang, Yu-Ying; Xu, Min; Li, Xiu-Ling; Polyhedron; vol. 101; (2015); p. 23 – 28;,
Metal catalyst and ligand design
Ligand Template Strategies for Catalyst Encapsulation – NCBI