Product Details of 32780-06-6. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one, is researched, Molecular C5H8O3, CAS is 32780-06-6, about A practical synthesis of (R)-(-)-γ-hydroxymethyl-γ-butyrolactone from natural glutamic acid. Author is Ho, Pak-Tsun; Davies, Nancy.
Tosylation of I (R = OH), prepared from natural (S)-(+)-glutamic acid, gave 96% I (R = p-MeC6H4SO3), which was treated with MeONa-MeOH to give quant. II, which, upon treatment with F3CCO2H at -10°, cyclized with complete inversion of configuration to give 86% III.
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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI